Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming

Hypoxia drives aging and promotes age-related cognition and hearing functional decline. Despite the role of erythrocytes in oxygen (O(2)) transport, their role in the onset of aging and age-related cognitive decline and hearing loss (HL) remains undetermined. Recent studies revealed that signaling t...

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Detalles Bibliográficos
Autores principales: Qiang, Qingfen, Manalo, Jeanne M., Sun, Hong, Zhang, Yujin, Song, Anren, Wen, Alexander Q., Wen, Y. Edward, Chen, Changhan, Liu, Hong, Cui, Ying, Nemkov, Travis, Reisz, Julie A., Edwards III, George, Perreira, Fred A., Kellems, Rodney E., Soto, Claudio, D’Alessandro, Angelo, Xia, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211187/
https://www.ncbi.nlm.nih.gov/pubmed/34138843
http://dx.doi.org/10.1371/journal.pbio.3001239

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