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The bioactivity of soluble Fas ligand is modulated by key amino acids of its stalk region

We have previously reported that the 26-amino acid N-terminus stalk region of soluble Fas ligand (sFasL), which is separate from its binding site, is required for its biological function. Here we investigate the mechanisms that link the structure of the sFasL stalk region with its function. Using si...

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Detalles Bibliográficos
Autores principales: Kajikawa, Osamu, Herrero, Raquel, Chow, Yu-Hua, Hung, Chi F., Matute-Bello, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211282/
https://www.ncbi.nlm.nih.gov/pubmed/34138914
http://dx.doi.org/10.1371/journal.pone.0253260