Cargando…
Advances of Antisense Oligonucleotide Technology in the Treatment of Hereditary Neurodegenerative Diseases
Antisense nucleic acids are single-stranded oligonucleotides that have been specially chemically modified, which can bind to RNA expressed by target genes through base complementary pairing and affect protein synthesis at the level of posttranscriptional processing or protein translation. In recent...
Autores principales: | Lin, Mengsi, Hu, Xinyi, Chang, Shiyi, Chang, Yan, Bian, Wenjun, Hu, Ruikun, Wang, Jing, Zhu, Qingwen, Qiu, Jiaying |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211492/ https://www.ncbi.nlm.nih.gov/pubmed/34211575 http://dx.doi.org/10.1155/2021/6678422 |
Ejemplares similares
-
Antisense Transcription in Loci Associated to Hereditary Neurodegenerative Diseases
por: Zucchelli, Silvia, et al.
Publicado: (2019) -
Tegsedi (Inotersen): An Antisense Oligonucleotide Approved for the Treatment of Adult Patients with Hereditary Transthyretin Amyloidosis
por: Gales, Luís
Publicado: (2019) -
Antisense Oligonucleotide Technologies to Combat Obesity and Fatty Liver Disease
por: Keating, Michael F., et al.
Publicado: (2022) -
Towards Personalized Allele-Specific Antisense Oligonucleotide Therapies for Toxic Gain-of-Function Neurodegenerative Diseases
por: Helm, Jacob, et al.
Publicado: (2022) -
Population Pharmacokinetic–Pharmacodynamic Modeling of Inotersen, an Antisense Oligonucleotide for Treatment of Patients with Hereditary Transthyretin Amyloidosis
por: Yu, Rosie Z., et al.
Publicado: (2020)