Cargando…

Antioral Squamous Cell Carcinoma Effects of Carvacrol via Inhibiting Inflammation, Proliferation, and Migration Related to Nrf2/Keap1 Pathway

OBJECTIVE: To observe the therapeutic effect of Carvacrol on oral squamous cell carcinoma (OSCC) and dissect underlying molecular mechanisms. METHODS: Keap1/Nrf2, NALP3, Vimentin, and E-cadherin expression was detected in OSCC and normal oral mucosa (NOM) tissues using immunofluorescence or western...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Hui, Xu, Xiaoliang, Wu, Ran, Bi, Lei, Zhang, Chunguang, Chen, Hui, Yang, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211494/ https://www.ncbi.nlm.nih.gov/pubmed/34212035 http://dx.doi.org/10.1155/2021/6616547

Ejemplares similares

MCU That Is Transcriptionally Regulated by Nrf2 Augments Malignant Biological Behaviors in Oral Squamous Cell Carcinoma Cells
por: Wu, Ran, et al.
Publicado: (2021)

Antioral Cancer Effects by the Nitrated [6,6,6]Tricycles Compound (SK1) In Vitro
por: Chen, Yan-Ning, et al.
Publicado: (2022)

Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion
por: Chen, Wen-Liang, et al.
Publicado: (2015)

Carvacrol suppresses proliferation and invasion in human oral squamous cell carcinoma
por: Dai, Wei, et al.
Publicado: (2016)

Clinical Significance of Keap1 and Nrf2 in Oral Squamous Cell Carcinoma
por: Huang, Cong-Fa, et al.
Publicado: (2013)

Antioxidant axis Nrf2-keap1-ARE in inhibition of alcoholic liver fibrosis by IL-22
por: Ni, Ya-Hui, et al.
Publicado: (2017)

Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis
por: Fan, Z, et al.
Publicado: (2017)

GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway
por: Li, Jingjing, et al.
Publicado: (2019)

Phloretin Prevents Diabetic Cardiomyopathy by Dissociating Keap1/Nrf2 Complex and Inhibiting Oxidative Stress
por: Ying, Yin, et al.
Publicado: (2018)

The KEAP1–NRF2 System in Cancer
por: Taguchi, Keiko, et al.
Publicado: (2017)

Keap1/Nrf2 Signaling Pathway
por: Sykiotis, Gerasimos P.
Publicado: (2021)

Nrf2 and Keap1 abnormalities in esophageal squamous cell carcinoma and association with the effect of chemoradiotherapy
por: Zhang, Jingze, et al.
Publicado: (2018)

Long noncoding RNA LINC00239 inhibits ferroptosis in colorectal cancer by binding to Keap1 to stabilize Nrf2
por: Han, Yuying, et al.
Publicado: (2022)

Desflurane Preconditioning Protects Against Renal Ischemia–Reperfusion Injury and Inhibits Inflammation and Oxidative Stress in Rats Through Regulating the Nrf2-Keap1-ARE Signaling Pathway
por: Zheng, Yan, et al.
Publicado: (2020)

The Keap1-Nrf2 System: A Mediator between Oxidative Stress and Aging
por: Yu, Chao, et al.
Publicado: (2021)

Structural basis of Keap1 interactions with Nrf2
por: Canning, Peter, et al.
Publicado: (2015)

Epigenetic Regulation of NRF2/KEAP1 by Phytochemicals
por: Bhattacharjee, Shamee, et al.
Publicado: (2020)

The KEAP1/NRF2 Signaling Pathway in Keratinization
por: Ishitsuka, Yosuke, et al.
Publicado: (2020)

The KEAP1-NRF2 System and Esophageal Cancer
por: Hirose, Wataru, et al.
Publicado: (2022)

Modulation of NRF2/KEAP1 Signaling in Preeclampsia
por: Tossetta, Giovanni, et al.
Publicado: (2023)

TNFAIP2 confers cisplatin resistance in head and neck squamous cell carcinoma via KEAP1/NRF2 signaling
por: Xu, Teng, et al.
Publicado: (2023)

Clinical implication of Keap1 and phosphorylated Nrf2 expression in hepatocellular carcinoma
por: Chen, Jiang, et al.
Publicado: (2016)

Nomilin targets the Keap1‐Nrf2 signalling and ameliorates the development of osteoarthritis
por: Xue, Xing‐He, et al.
Publicado: (2020)

Carvacrol
por: Bogue, E. A.
Publicado: (1874)

DDRGK1 Enhances Osteosarcoma Chemoresistance via Inhibiting KEAP1‐Mediated NRF2 Ubiquitination
por: Wang, Xin, et al.
Publicado: (2023)

EETs alleviate alveolar epithelial cell senescence by inhibiting endoplasmic reticulum stress through the Trim25/Keap1/Nrf2 axis
por: Zhang, Chen-Yu, et al.
Publicado: (2023)

KEAP1 and done? Targeting the NRF2 pathway with sulforaphane
por: Dinkova-Kostova, Albena T., et al.
Publicado: (2017)

WDR23 regulates NRF2 independently of KEAP1
por: Lo, Jacqueline Y., et al.
Publicado: (2017)

Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway
por: Hassanein, Emad H. M., et al.
Publicado: (2020)

Nrf2/Keap1/ARE signaling: Towards specific regulation
por: Ulasov, Alexey V., et al.
Publicado: (2022)

The KEAP1-NRF2 System in Healthy Aging and Longevity
por: Matsumaru, Daisuke, et al.
Publicado: (2021)

Molecular Basis of the KEAP1-NRF2 Signaling Pathway
por: Suzuki, Takafumi, et al.
Publicado: (2023)

Insights into the Regulation of GFR by the Keap1-Nrf2 Pathway
por: Kidokoro, Kengo, et al.
Publicado: (2023)

The potential roles of Nrf2/Keap1 signaling in anticancer drug interactions
por: Wang, Jingya, et al.
Publicado: (2021)

Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway
por: Lin, Yajuan, et al.
Publicado: (2021)

Unraveling the Biosynthesis of Carvacrol in Different Tissues of Origanum vulgare
por: Hao, Yuanpeng, et al.
Publicado: (2022)

Inhibition of MAGL activates the Keap1/Nrf2 pathway to attenuate glucocorticoid‐induced osteonecrosis of the femoral head
por: Yang, Ning, et al.
Publicado: (2021)

Activation of NRF2 by dexamethasone in ataxia telangiectasia cells involves KEAP1 inhibition but not the inhibition of p38
por: Biagiotti, Sara, et al.
Publicado: (2019)

Flos puerariae ameliorates the intestinal inflammation of Drosophila via modulating the Nrf2/Keap1, JAK-STAT and Wnt signaling
por: Yang, Shipei, et al.
Publicado: (2022)

Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway
por: Copple, Ian M., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_hrc14drso6o6km412p0q6hf2ep