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17β-Estradiol Attenuates LPS-Induced Macrophage Inflammation In Vitro and Sepsis-Induced Vascular Inflammation In Vivo by Upregulating miR-29a-5p Expression

Excessive release of cytokines such as IL-1β and other inflammatory mediators synthesized and secreted by macrophages is the fundamental link of uncontrolled inflammatory response in sepsis. 17β-Estradiol (E2) plays anti-inflammatory and vascular protective effects by regulating leukocyte infiltrati...

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Detalles Bibliográficos
Autores principales:	Zhang, Man-li, Chen, Hui, Yang, Zhan, Zhang, Man-na, Wang, Xia, Zhao, Kun, Li, Xuan, Xiu, Nan, Tong, Fei, Wang, Ya-xuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211527/ https://www.ncbi.nlm.nih.gov/pubmed/34220338 http://dx.doi.org/10.1155/2021/9921897

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