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Amyloid-Beta Mediates Homeostatic Synaptic Plasticity

The physiological role of the amyloid-precursor protein (APP) is insufficiently understood. Recent work has implicated APP in the regulation of synaptic plasticity. Substantial evidence exists for a role of APP and its secreted ectodomain APPsα in Hebbian plasticity. Here, we addressed the relevance...

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Detalles Bibliográficos
Autores principales: Galanis, Christos, Fellenz, Meike, Becker, Denise, Bold, Charlotte, Lichtenthaler, Stefan F., Müller, Ulrike C., Deller, Thomas, Vlachos, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211553/
https://www.ncbi.nlm.nih.gov/pubmed/33926999
http://dx.doi.org/10.1523/JNEUROSCI.1820-20.2021

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