Cargando…

Nuclear scaffold protein p54(nrb)/NONO facilitates the hypoxia-enhanced progression of hepatocellular carcinoma

Hypoxia and related oxidative stress are closely related to the development and treatment of hepatocellular carcinoma (HCC). However, the mechanism mediated by hypoxia in HCC has not yet been elucidated. Here, we found multifunction scaffold protein p54(nrb)/NONO exerted pleiotropic effects to regul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Mengqin, Zhang, Ruixue, Jia, Wenzhi, Zhu, Zongping, Zhao, Xiaoping, Zhao, Li, Huang, Gang, Liu, Jianjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211563/ https://www.ncbi.nlm.nih.gov/pubmed/34079086 http://dx.doi.org/10.1038/s41388-021-01848-9

Ejemplares similares

RNA-binding protein p54(nrb)/NONO potentiates nuclear EGFR-mediated tumorigenesis of triple-negative breast cancer
por: Shen, Mengqin, et al.
Publicado: (2022)

p54nrb/NonO and PSF promote U snRNA nuclear export by accelerating its export complex assembly
por: Izumi, Hiroto, et al.
Publicado: (2014)

Overexpression of p54(nrb)/NONO induces differential EPHA6 splicing and contributes to castration-resistant prostate cancer growth
por: Yamamoto, Ryuji, et al.
Publicado: (2018)

Regulation of PCGEM1 by p54/nrb in prostate cancer
por: Ho, Tsui-Ting, et al.
Publicado: (2016)

Immunodetection of nmt55/p54(nrb) isoforms in human breast cancer
por: Pavao, Matthew, et al.
Publicado: (2001)

Promoter-Dependent Translation Controlled by p54(nrb) and hnRNPM during Myoblast Differentiation
por: Ainaoui, Nadera, et al.
Publicado: (2015)

2′-Fluoro-modified phosphorothioate oligonucleotide can cause rapid degradation of P54nrb and PSF
por: Shen, Wen, et al.
Publicado: (2015)

Kinetic and subcellular analysis of PS-ASO/protein interactions with P54nrb and RNase H1
por: Vickers, Timothy A, et al.
Publicado: (2019)

Depletion of NEAT1 lncRNA attenuates nucleolar stress by releasing sequestered P54nrb and PSF to facilitate c-Myc translation
por: Shen, Wen, et al.
Publicado: (2017)

Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance
por: Li, Shuyi, et al.
Publicado: (2009)

HDAC8-dependent deacetylation of PKM2 directs nuclear localization and glycolysis to promote proliferation in hepatocellular carcinoma
por: Zhang, Ruixue, et al.
Publicado: (2020)

Prognostic values of ALDOB expression and (18)F-FDG PET/CT in hepatocellular carcinoma
por: Jia, Wenzhi, et al.
Publicado: (2022)

The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions
por: Eichler, Madeleine, et al.
Publicado: (2022)

The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffold
por: Knott, Gavin J., et al.
Publicado: (2016)

Altered stoichiometry and nuclear delocalization of NonO and PSF promote cellular senescence
por: Huang, Ching-Jung, et al.
Publicado: (2016)

SIRT5‐mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer
por: Shi, Liang, et al.
Publicado: (2018)

Transcriptional silencing of fetal hemoglobin expression by NonO
por: Li, Xinyu, et al.
Publicado: (2021)

NONO and tumorigenesis: More than splicing
por: Feng, Peifu, et al.
Publicado: (2020)

The suitability of NONO-TFE3 dual-fusion FISH assay as a diagnostic tool for NONO-TFE3 renal cell carcinoma
por: Liu, Ning, et al.
Publicado: (2020)

ACLY facilitates colon cancer cell metastasis by CTNNB1
por: Wen, Jun, et al.
Publicado: (2019)

Targeting the splicing factor NONO inhibits GBM progression through GPX1 intron retention
por: Wang, Xu, et al.
Publicado: (2022)

NONO promotes hepatocellular carcinoma progression by enhancing fatty acids biosynthesis through interacting with ACLY mRNA
por: Ding, Hongda, et al.
Publicado: (2020)

The Conserved LncRNA DIO3OS Restricts Hepatocellular Carcinoma Stemness by Interfering with NONO‐Mediated Nuclear Export of ZEB1 mRNA
por: Hou, Ya‐Rui, et al.
Publicado: (2023)

PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer
por: Yin, Xin-Ke, et al.
Publicado: (2021)

PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma
por: Yang, Hao, et al.
Publicado: (2016)

Persistent diarrhoea in a 5-month-old baby carrying Vibrio cholerae nonO1/nonO139 producing Haitian cholera toxin
por: Kumar, P., et al.
Publicado: (2017)

The regulation of NONO by USP11 via deubiquitination is linked to the proliferation of melanoma cells
por: Feng, Peifu, et al.
Publicado: (2020)

Met is involved in TIGAR-regulated metastasis of non-small-cell lung cancer
por: Shen, Mengqin, et al.
Publicado: (2018)

SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability
por: Petti, Eleonora, et al.
Publicado: (2019)

Molecular Modelling of NONO and SFPQ Dimerization Process and RNA Recognition Mechanism
por: Laurenzi, Tommaso, et al.
Publicado: (2022)

Stabilization of SAMHD1 by NONO is crucial for Ara-C resistance in AML
por: Zhang, Feifei, et al.
Publicado: (2022)

A novel NONO variant that causes developmental delay and cardiac phenotypes
por: Itai, Toshiyuki, et al.
Publicado: (2023)

In vivo Proximity Labeling of Nuclear and Nucleolar Proteins by a Stably Expressed, DNA Damage-Responsive NONO-APEX2 Fusion Protein
por: Trifault, Barbara, et al.
Publicado: (2022)

Rasd1 Modulates the Coactivator Function of NonO in the Cyclic AMP Pathway
por: Ong, Shufen Angeline, et al.
Publicado: (2011)

OGA is associated with deglycosylation of NONO and the KU complex during DNA damage repair
por: Cui, Yaqi, et al.
Publicado: (2021)

AC016745.3 Regulates the Transcription of AR Target Genes by Antagonizing NONO
por: Lu, Yali, et al.
Publicado: (2021)

First report on the occurrence of Vibrio cholerae nonO1/nonO139 in natural and artificial lakes and ponds in Serbia: Evidence for a long‐distance transfer of strains and the presence of Vibrio paracholerae
por: Rehm, Carmen, et al.
Publicado: (2023)

54th International Winter Meeting on Nuclear Physics
por: Collective
Publicado: (2016)

Small ubiquitin-like modifier 1 modification of pyruvate kinase M2 promotes aerobic glycolysis and cell proliferation in A549 human lung cancer cells
por: An, Shuxian, et al.
Publicado: (2018)

Hypoxia-induced LINC00674 facilitates hepatocellular carcinoma progression by activating the NOX1/mTOR signaling pathway
por: Zhu, Ning, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_092fcb7h95208ln9iot1l4tm0a