The Influence of Age on Central Effects of Methylnaltrexone in Patients with Opioid-Induced Constipation

BACKGROUND: Methylnaltrexone, a peripherally acting µ-opioid receptor antagonist approved for the treatment of opioid-induced constipation (OIC), has restricted diffusion across the blood–brain barrier (BBB) and has not been demonstrated to impact opioid-induced central analgesia. Age-related change...

Descripción completa

Detalles Bibliográficos
Autores principales: Liao, Solomon S., Slatkin, Neal E., Stambler, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211613/
https://www.ncbi.nlm.nih.gov/pubmed/33788162
http://dx.doi.org/10.1007/s40266-021-00850-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211613/
https://www.ncbi.nlm.nih.gov/pubmed/33788162
http://dx.doi.org/10.1007/s40266-021-00850-w

Ejemplares similares