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Generation of hematopoietic stem/progenitor cells with sickle cell mutation from induced pluripotent stem cell in serum-free system

INTRODUCTION: Sickle cell disease (SCD) is a monogenic disease and it is estimated that 300,000 infants are born annually with it. Most treatments available are only palliative, whereas the allogeneic hematopoietic stem cell transplantation offers the only potential cure for SCD. OBJECTIVE: Generati...

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Detalles Bibliográficos
Autores principales:	Paes, Bárbara C.M.F., Stabeli, Luiza C.J.R., Costa, Péricles N.M., Orellana, Maristela Delgado, Kashima, Simone, Covas, Dimas Tadeu, Picanço-Castro, Virgínia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Hematologia e Hemoterapia 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211631/ https://www.ncbi.nlm.nih.gov/pubmed/32229108 http://dx.doi.org/10.1016/j.htct.2020.01.005

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