Cargando…

HER2-antigen-specific humoral immune response in breast cancer lymphocytes transplanted in hu-PBL hIL-4 NOG mice

The status of humoral immunity of cancer patients is not clear compared to cellular immunity because the ability of specific antibody production is difficult to analyze in vitro. We previously developed a humanized mouse model to evaluate antigen-specific antibody production by transplanting human p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ohno, Yusuke, Ohshima, Shino, Miyamoto, Asuka, Kametani, Fuyuki, Ito, Ryoji, Tsuda, Banri, Kasama, Yukie, Nakada, Shunsuke, Kashiwagi, Hirofumi, Seki, Toshiro, Yasuda, Atsushi, Ando, Kiyoshi, Ito, Mamoru, Tokuda, Yutaka, Kametani, Yoshie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211648/ https://www.ncbi.nlm.nih.gov/pubmed/34140620 http://dx.doi.org/10.1038/s41598-021-92311-y

Ejemplares similares

NOG-hIL-4-Tg, a new humanized mouse model for producing tumor antigen-specific IgG antibody by peptide vaccination
por: Kametani, Yoshie, et al.
Publicado: (2017)

Humanized Mice as an Effective Evaluation System for Peptide Vaccines and Immune Checkpoint Inhibitors
por: Kametani, Yoshie, et al.
Publicado: (2019)

High-progesterone environment preserves T cell competency by evading glucocorticoid effects on immune regulation
por: Kashiwagi, Hirofumi, et al.
Publicado: (2022)

Construction of the systemic anticancer immune environment in tumour-bearing humanized mouse by using liposome-encapsulated anti-programmed death ligand 1 antibody-conjugated progesterone
por: Kametani, Yoshie, et al.
Publicado: (2023)

FRI374 Immunomodulatory Effects Of Progesterone And Glucocorticoids In Pregnancy Immunity
por: Yasuda, Atsushi, et al.
Publicado: (2023)

B-cell populations are expanded in breast cancer patients compared with healthy controls
por: Tsuda, Banri, et al.
Publicado: (2017)

Coccomyxa sp.KJ extract affects the fate of T cells stimulated by toxic shock syndrome toxin‐1, a superantigen secreted by Staphylococcus aureus
por: Ohshima, Shino, et al.
Publicado: (2022)

Human PZP and common marmoset A2ML1 as pregnancy related proteins
por: Kashiwagi, Hirofumi, et al.
Publicado: (2020)

Generation of Human Immunosuppressive Myeloid Cell Populations in Human Interleukin-6 Transgenic NOG Mice
por: Hanazawa, Asami, et al.
Publicado: (2018)

Enhanced Antibody Responses in a Novel NOG Transgenic Mouse with Restored Lymph Node Organogenesis
por: Takahashi, Takeshi, et al.
Publicado: (2018)

Human PBMC-transferred murine MHC class I/II-deficient NOG mice enable long-term evaluation of human immune responses
por: Yaguchi, Tomonori, et al.
Publicado: (2017)

Precise immunological evaluation rationalizes the design of a self-adjuvanting vaccine composed of glycan antigen, TLR1/2 ligand, and T-helper cell epitope
por: Chang, Tsung-Che, et al.
Publicado: (2022)

Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease
por: Kametani, Fuyuki, et al.
Publicado: (2018)

Protection against Amyloid-β Oligomer Neurotoxicity by Small Molecules with Antioxidative Properties: Potential for the Prevention of Alzheimer’s Disease Dementia
por: Araki, Wataru, et al.
Publicado: (2022)

Use of Hu-PBL Mice to Study Pathogenesis of Human-Restricted Viruses
por: Brunetti, Jesús Emanuel, et al.
Publicado: (2023)

MHC class I/II deficient NOG mice are useful for analysis of human T/B cell responses for human tumor immunology research
por: Yaguchi, Tomonori, et al.
Publicado: (2013)

NOD-Rag2(null) IL-2Rγ(null) Mice: An Alternative to NOG Mice for Generation of Humanized Mice
por: Katano, Ikumi, et al.
Publicado: (2014)

Mutations in the β-amyloid precursor protein in familial Alzheimer’s disease increase Aβ oligomer production in cellular models
por: Ohshima, Yoichi, et al.
Publicado: (2018)

Genetic Association between Farrowing Rates and Swine Leukocyte Antigen Alleles or Haplotypes in Microminipigs
por: Ando, Asako, et al.
Publicado: (2022)

Long-term maintenance of peripheral blood derived human NK cells in a novel human IL-15- transgenic NOG mouse
por: Katano, Ikumi, et al.
Publicado: (2017)

The development of vaccines against SARS corona virus in mice and SCID-PBL/hu mice
por: Okada, Masaji, et al.
Publicado: (2005)

Stillbirth rates and their association with swine leucocyte antigen class II haplotypes in Microminipigs
por: Imaeda, Noriaki, et al.
Publicado: (2021)

Development of vaccines and passive immunotherapy against SARS corona virus using SCID-PBL/hu mouse models
por: Okada, Masaji, et al.
Publicado: (2007)

Critical Contribution of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail) to Apoptosis of Human Cd4(+)T Cells in HIV-1–Infected Hu-Pbl-Nod-Scid Mice
por: Miura, Yoshiharu, et al.
Publicado: (2001)

Preparation and characterization of monoclonal antibodies recognizing two CD4 isotypes of Microminipigs
por: Ohshima, Shino, et al.
Publicado: (2020)

Genetic Association between Swine Leukocyte antigen Class II Haplotypes and Reproduction Traits in Microminipigs
por: Ando, Asako, et al.
Publicado: (2019)

Anti-SCID mouse reactivity shapes the human CD4+ T cell repertoire in hu-PBL-SCID chimeras
Publicado: (1994)

Reconstitution of huPBL-NSG Mice with Donor-Matched Dendritic Cells Enables Antigen-Specific T-cell Activation
por: Harui, Airi, et al.
Publicado: (2010)

Human-derived IgG level as an indicator for EBV-associated lymphoma model in Hu-PBL/SCID chimeras
por: Tang, Yunlian, et al.
Publicado: (2011)

Development of Vaccines and Passive Immunotherapy Against Sars Coronavirus Using Mouse and Scid-PBL/hu Mouse Models
por: Okada, Masaji, et al.
Publicado: (2006)

Hereditary Fibrinogen Aα-Chain Amyloidosis in Asia: Clinical and Molecular Characteristics
por: Yazaki, Masahide, et al.
Publicado: (2018)

Generation of Novel Human Red Blood Cell-Bearing Humanized Mouse Models Based on C3-Deficient NOG Mice
por: Yamaguchi, Takuya, et al.
Publicado: (2021)

Production of a Locus- and Allele-Specific Monoclonal Antibody for the Characterization of SLA-1*0401 mRNA and Protein Expression Levels in MHC-Defined Microminipigs
por: Kametani, Yoshie, et al.
Publicado: (2016)

Dysregulation of the progranulin-driven autophagy-lysosomal pathway mediates secretion of the nuclear protein TDP-43
por: Tanaka, Yoshinori, et al.
Publicado: (2023)

Volatile Anesthetic Sevoflurane Precursor 1,1,1,3,3,3-Hexafluoro-2-Propanol (HFIP) Exerts an Anti-Prion Activity in Prion-Infected Culture Cells
por: Shimizu, Takuto, et al.
Publicado: (2021)

Improved Detection of in vivo Human NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity Using a Novel NOG-FcγR-Deficient Human IL-15 Transgenic Mouse
por: Katano, Ikumi, et al.
Publicado: (2020)

Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons
por: Mamada, Naomi, et al.
Publicado: (2015)

Intratumoral IL-12 Gene Therapy Inhibits Tumor Growth In A HCC-Hu-PBL-NOD/SCID Murine Model
por: Zhou, Zhi-Feng, et al.
Publicado: (2019)

The intraspleen huPBL NOD/SCID model to study the human HIV-specific antibody response selected in the course of natural infection
por: Steyaert, Sophia, et al.
Publicado: (2007)

Glucocorticoid Receptor Antagonist Administration Prevents Adrenal Gland Atrophy in an ACTH-Independent Cushing's Syndrome Rat Model
por: Yasuda, Atsushi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_evijr3ag7r3l4548l37jar9qvd