Cargando…

Paired analysis of tumor mutation burden for lung adenocarcinoma and associated idiopathic pulmonary fibrosis

Genetic alterations underlying the development of lung cancer in individuals with idiopathic pulmonary fibrosis (IPF) have remained unclear. To explore whether genetic alterations in IPF tissue contribute to the development of IPF-associated lung cancer, we here evaluated tumor mutation burden (TMB)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoneshima, Yasuto, Iwama, Eiji, Matsumoto, Shingo, Matsubara, Taichi, Tagawa, Testuzo, Ota, Keiichi, Tanaka, Kentaro, Takenoyama, Mitsuhiro, Okamoto, Tatsuro, Goto, Koichi, Mori, Masaki, Okamoto, Isamu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211684/ https://www.ncbi.nlm.nih.gov/pubmed/34140559 http://dx.doi.org/10.1038/s41598-021-92098-y

Ejemplares similares

Paired genetic analysis by next‐generation sequencing of lung cancer and associated idiopathic pulmonary fibrosis
por: Otsubo, Kohei, et al.
Publicado: (2020)

Immunostimulatory oncolytic activity of coxsackievirus A11 in human malignant pleural mesothelioma
por: Okamura, Koji, et al.
Publicado: (2022)

Regulation of PD-L1 expression in non–small cell lung cancer by interleukin-1β
por: Hirayama, Aiko, et al.
Publicado: (2023)

Association of thyroid transcription factor-1 (TTF-1) expression with efficacy of PD-1/PD-L1 inhibitors plus pemetrexed and platinum chemotherapy in advanced non-squamous non-small cell lung cancer
por: Ibusuki, Ritsu, et al.
Publicado: (2022)

Association of Mps one binder kinase activator 1 (MOB1) expression with poor disease‐free survival in individuals with non‐small cell lung cancer
por: Ando, Nobuhisa, et al.
Publicado: (2020)

Evaluation of appropriate conditions for Oncomine DxTT testing of FFPE specimens for driver gene alterations in non–small cell lung cancer
por: Iwama, Eiji, et al.
Publicado: (2023)

A propensity score-matched analysis of the impact of statin therapy on the outcomes of patients with non-small-cell lung cancer receiving anti-PD-1 monotherapy: a multicenter retrospective study
por: Takada, Kazuki, et al.
Publicado: (2022)

MicroRNA‐326 negatively regulates CD155 expression in lung adenocarcinoma
por: Nakanishi, Takayuki, et al.
Publicado: (2023)

(18)F-FDG uptake in PET/CT is a potential predictive biomarker of response to anti-PD-1 antibody therapy in non-small cell lung cancer
por: Takada, Kazuki, et al.
Publicado: (2019)

Detection of identical T cell clones in peritumoral pleural effusion and pneumonitis lesions in a cancer patient during immune-checkpoint blockade
por: Tanaka, Kentaro, et al.
Publicado: (2018)

Cohesion between pulmonary artery and bronchus after immune checkpoint inhibitor therapy in a lung cancer patient
por: Takamori, Shinkichi, et al.
Publicado: (2020)

Pleuroparenchymal fibroelastosis secondary to autologous peripheral blood stem cell transplantation: A case report
por: Egashira, Ayaka, et al.
Publicado: (2023)

Increased plasma levels of damage-associated molecular patterns during systemic anticancer therapy in patients with advanced lung cancer
por: Inoue, Hiroyuki, et al.
Publicado: (2021)

Development of anaplastic lymphoma kinase (ALK) inhibitors and molecular diagnosis in ALK rearrangement-positive lung cancer
por: Iwama, Eiji, et al.
Publicado: (2014)

HTLV‐1 seropositive patients with lung cancer treated with PD‐1 inhibitors
por: Yoneshima, Yasuto, et al.
Publicado: (2020)

The clinical impact of concomitant medication use on the outcome of postoperative recurrent non-small-cell lung cancer in patients receiving immune checkpoint inhibitors
por: Takada, Kazuki, et al.
Publicado: (2022)

Prognostic value of postoperative decrease in serum albumin on surgically resected early-stage non-small cell lung carcinoma: A multicenter retrospective study
por: Kinoshita, Fumihiko, et al.
Publicado: (2021)

Exploration of resistance mechanisms for epidermal growth factor receptor‐tyrosine kinase inhibitors based on plasma analysis by digital polymerase chain reaction and next‐generation sequencing
por: Iwama, Eiji, et al.
Publicado: (2018)

Phase 3 study of ceritinib vs chemotherapy in ALK-rearranged NSCLC patients previously treated with chemotherapy and crizotinib (ASCEND-5): Japanese subset
por: Kiura, Katsuyuki, et al.
Publicado: (2018)

PICT1 expression is a poor prognostic factor in non-small cell lung cancer
por: Okamura, Kyoko, et al.
Publicado: (2014)

Clinical significance of preoperative inflammatory markers in non-small cell lung cancer patients: A multicenter retrospective study
por: Takada, Kazuki, et al.
Publicado: (2020)

Highly sensitive and quantitative evaluation of the EGFR T790M mutation by nanofluidic digital PCR
por: Iwama, Eiji, et al.
Publicado: (2015)

Mutational signatures in squamous cell carcinoma of the lung
por: Osoegawa, Atsushi, et al.
Publicado: (2021)

Association between peripheral blood markers and immune-related factors on tumor cells in patients with resected primary lung adenocarcinoma
por: Takada, Kazuki, et al.
Publicado: (2019)

Visualization and quantitation of epidermal growth factor receptor homodimerization and activation with a proximity ligation assay
por: Ota, Keiichi, et al.
Publicado: (2017)

Phase I study of salazosulfapyridine in combination with cisplatin and pemetrexed for advanced non‐small‐cell lung cancer
por: Otsubo, Kohei, et al.
Publicado: (2017)

Does short-term cessation of smoking before lung resections reduce the risk of complications?
por: Takenaka, Tomoyoshi, et al.
Publicado: (2020)

Addition of bevacizumab enhances antitumor activity of erlotinib against non-small cell lung cancer xenografts depending on VEGF expression
por: Li, Heyan, et al.
Publicado: (2014)

Brain cavernous hemangioma mimicking radiation‐induced necrosis in a patient with non‐small cell lung cancer
por: Takamori, Shinkichi, et al.
Publicado: (2020)

The impact of immune-inflammation-nutritional parameters on the prognosis of non-small cell lung cancer patients treated with atezolizumab
por: Matsubara, Taichi, et al.
Publicado: (2020)

Histological conversion from adenocarcinoma to small cell carcinoma of the lung after treatment with an immune checkpoint inhibitor: a case report
por: Miura, Naoko, et al.
Publicado: (2020)

Atezolizumab-Induced Aseptic Meningitis in Patients with NSCLC
por: Toyozawa, Ryo, et al.
Publicado: (2020)

Lorlatinib-Induced Pulmonary Embolism in a Patient With an ALK-Positive NSCLC
por: Toyozawa, Ryo, et al.
Publicado: (2020)

Assessment of the albumin-bilirubin grade as a prognostic factor in patients with non-small-cell lung cancer receiving anti-PD-1-based therapy
por: Takada, K., et al.
Publicado: (2021)

Anti–PD-1 Monotherapy for Advanced NSCLC Patients with Older Age or Those with Poor Performance Status
por: Matsubara, Taichi, et al.
Publicado: (2021)

Dramatic intracranial response to tepotinib in a patient with lung adenocarcinoma harboring MET exon 14 skipping mutation
por: Takamori, Shinkichi, et al.
Publicado: (2021)

Successful treatment of locally advanced lung cancer using late concurrent chemoradiation therapy administered after immune checkpoint inhibitor plus platinum chemotherapy
por: Matsubara, Taichi, et al.
Publicado: (2021)

Scedosporium apiospermum lung disease in a patient with nontuberculous mycobacteria
por: Ogata, Hiroaki, et al.
Publicado: (2020)

Further Characterization of the Human Adrenal‐derived P‐GIycoprotein Recognized by Monoclonal Antibody MRK 16 Reacting with Only Human P‐Glycoprotein
por: Sugawara, Isamu, et al.
Publicado: (1989)

Prospective observational study of nutritional/immunologic indices as predictive biomarkers for the response to anti-PD-1 drugs in non-small cell lung cancer (ICI-PREDICT study)
por: Takamori, Shinkichi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pkqtf18luvuall38b3ai2gvncr