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Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified

Peripheral T-cell lymphoma (PTCL) is a heterogeneous group of non-Hodgkin lymphomas with poor prognosis. Up to 30% of PTCL lack distinctive features and are classified as PTCL, not otherwise specified (PTCL-NOS). To further improve our understanding of the genetic landscape and biology of PTCL-NOS,...

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Detalles Bibliográficos
Autores principales: Debackere, Koen, Marcelis, Lukas, Demeyer, Sofie, Vanden Bempt, Marlies, Mentens, Nicole, Gielen, Olga, Jacobs, Kris, Broux, Michael, Verhoef, Gregor, Michaux, Lucienne, Graux, Carlos, Wlodarska, Iwona, Gaulard, Philippe, de Leval, Laurence, Tousseyn, Thomas, Cools, Jan, Dierickx, Daan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211700/
https://www.ncbi.nlm.nih.gov/pubmed/34140493
http://dx.doi.org/10.1038/s41467-021-24037-4