Oxaliplatin Depolarizes the IB4(–) Dorsal Root Ganglion Neurons to Drive the Development of Neuropathic Pain Through TRPM8 in Mice

Use of chemotherapy drug oxaliplatin is associated with painful peripheral neuropathy that is exacerbated by cold. Remodeling of ion channels including TRP channels in dorsal root ganglion (DRG) neurons contribute to the sensory hypersensitivity following oxaliplatin treatment in animal models. Howe...

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Detalles Bibliográficos
Autores principales: Wu, Bin, Su, Xiaolin, Zhang, Wentong, Zhang, Yi-Hong, Feng, Xinghua, Ji, Yong-Hua, Tan, Zhi-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211750/
https://www.ncbi.nlm.nih.gov/pubmed/34149356
http://dx.doi.org/10.3389/fnmol.2021.690858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211750/
https://www.ncbi.nlm.nih.gov/pubmed/34149356
http://dx.doi.org/10.3389/fnmol.2021.690858

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