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Oxaliplatin Depolarizes the IB4(–) Dorsal Root Ganglion Neurons to Drive the Development of Neuropathic Pain Through TRPM8 in Mice
Use of chemotherapy drug oxaliplatin is associated with painful peripheral neuropathy that is exacerbated by cold. Remodeling of ion channels including TRP channels in dorsal root ganglion (DRG) neurons contribute to the sensory hypersensitivity following oxaliplatin treatment in animal models. Howe...
Autores principales: | Wu, Bin, Su, Xiaolin, Zhang, Wentong, Zhang, Yi-Hong, Feng, Xinghua, Ji, Yong-Hua, Tan, Zhi-Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211750/ https://www.ncbi.nlm.nih.gov/pubmed/34149356 http://dx.doi.org/10.3389/fnmol.2021.690858 |
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