Suppression of mitochondrial ROS by prohibitin drives glioblastoma progression and therapeutic resistance

Low levels of reactive oxygen species (ROS) are crucial for maintaining cancer stem cells (CSCs) and their ability to resist therapy, but the ROS regulatory mechanisms in CSCs remains to be explored. Here, we discover that prohibitin (PHB) specifically regulates mitochondrial ROS production in gliom...

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Detalles Bibliográficos
Autores principales: Huang, Haohao, Zhang, Songyang, Li, Yuanyuan, Liu, Zhaodan, Mi, Lanjuan, Cai, Yan, Wang, Xinzheng, Chen, Lishu, Ran, Haowen, Xiao, Dake, Li, Fangye, Wu, Jiaqi, Li, Tingting, Han, Qiuying, Chen, Liang, Pan, Xin, Li, Huiyan, Li, Tao, He, Kun, Li, Ailing, Zhang, Xuemin, Zhou, Tao, Xia, Qing, Man, Jianghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211793/
https://www.ncbi.nlm.nih.gov/pubmed/34140524
http://dx.doi.org/10.1038/s41467-021-24108-6

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