3D genome alterations associated with dysregulated HOXA13 expression in high-risk T-lineage acute lymphoblastic leukemia

3D genome alternations can dysregulate gene expression by rewiring enhancer-promoter interactions and lead to diseases. We report integrated analyses of 3D genome alterations and differential gene expressions in 18 newly diagnosed T-lineage acute lymphoblastic leukemia (T-ALL) patients and 4 healthy...

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Detalles Bibliográficos
Autores principales: Yang, Lu, Chen, Fengling, Zhu, Haichuan, Chen, Yang, Dong, Bingjie, Shi, Minglei, Wang, Weitao, Jiang, Qian, Zhang, Leping, Huang, Xiaojun, Zhang, Michael Q., Wu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211852/
https://www.ncbi.nlm.nih.gov/pubmed/34140506
http://dx.doi.org/10.1038/s41467-021-24044-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211852/
https://www.ncbi.nlm.nih.gov/pubmed/34140506
http://dx.doi.org/10.1038/s41467-021-24044-5

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