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Unravelling cytosolic delivery of cell penetrating peptides with a quantitative endosomal escape assay
Cytosolic transport is an essential requirement but a major obstacle to efficient delivery of therapeutic peptides, proteins and nucleic acids. Current understanding of cytosolic delivery mechanisms remains limited due to a significant number of conflicting reports, which are compounded by low sensi...
Autores principales: | Teo, Serena L. Y., Rennick, Joshua J., Yuen, Daniel, Al-Wassiti, Hareth, Johnston, Angus P. R., Pouton, Colin W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211857/ https://www.ncbi.nlm.nih.gov/pubmed/34140497 http://dx.doi.org/10.1038/s41467-021-23997-x |
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