Sulfiredoxin-1 attenuates injury and inflammation in acute pancreatitis through the ROS/ER stress/Cathepsin B axis

Acinar cell injury and the inflammatory response are critical bioprocesses of acute pancreatitis (AP). We investigated the role and underlying mechanism of sulfiredoxin-1 (Srxn1) in AP. Mild AP was induced by intraperitoneal injection of cerulein and severe AP was induced by partial duct ligation wi...

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Detalles Bibliográficos
Autores principales: He, Jun, Ma, Miaomiao, Li, Daming, Wang, Kunpeng, Wang, Qiuguo, Li, Qiuguo, He, Hongye, Zhou, Yan, Li, Qinglong, Hou, Xuyang, Yang, Leping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211864/
https://www.ncbi.nlm.nih.gov/pubmed/34140464
http://dx.doi.org/10.1038/s41419-021-03923-1

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