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Strabismus and Artificial Intelligence App: Optimizing Diagnostic and Accuracy

PURPOSE: Clinical evaluation of eye versions plays an important role in the diagnosis of special strabismus. Despite the importance of versions, they are not standardized in clinical practice because they are subjective. Assuming that objectivity confers accuracy, this research aims to create an art...

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Autores principales: de Figueiredo, Laura Alves, Dias, João Victor Pacheco, Polati, Mariza, Carricondo, Pedro Carlos, Debert, Iara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212438/
https://www.ncbi.nlm.nih.gov/pubmed/34137838
http://dx.doi.org/10.1167/tvst.10.7.22
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author de Figueiredo, Laura Alves
Dias, João Victor Pacheco
Polati, Mariza
Carricondo, Pedro Carlos
Debert, Iara
author_facet de Figueiredo, Laura Alves
Dias, João Victor Pacheco
Polati, Mariza
Carricondo, Pedro Carlos
Debert, Iara
author_sort de Figueiredo, Laura Alves
collection PubMed
description PURPOSE: Clinical evaluation of eye versions plays an important role in the diagnosis of special strabismus. Despite the importance of versions, they are not standardized in clinical practice because they are subjective. Assuming that objectivity confers accuracy, this research aims to create an artificial intelligence app that can classify the eye versions into nine positions of gaze. METHODS: We analyzed photos of 110 strabismus patients from an outpatient clinic of a tertiary hospital at nine gazes. For each photo, the gaze was identified, and the corresponding version was rated by the same examiner during patient evaluation. RESULTS: The images were standardized by using the OpenCV library in Python language, so that the patient's eyes were located and sent to a multilabel model through the Keras framework regardless of the photo orientation. Then, the model was trained for each combination of the following groupings: eyes (left, right), gaze (1 to 9), and version (−4 to 4). Resnet50 was used as the neural network architecture, and the Data Augmentation technique was applied. For quick inference via web browser, the SteamLit app framework was employed. For use in Mobiles, the finished model was exported for use in through the Tensorflow Lite converter. CONCLUSIONS: The results showed that the mobile app might be applied to complement evaluation of ocular motility based on objective classification of ocular versions. However, further exploratory research and validations are required. TRANSLATIONAL RELEVANCE: Apart from the traditional clinical practice method, professionals will be able to envisage an easy-to-apply support app, to increase diagnostic accuracy.
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spelling pubmed-82124382021-06-22 Strabismus and Artificial Intelligence App: Optimizing Diagnostic and Accuracy de Figueiredo, Laura Alves Dias, João Victor Pacheco Polati, Mariza Carricondo, Pedro Carlos Debert, Iara Transl Vis Sci Technol Article PURPOSE: Clinical evaluation of eye versions plays an important role in the diagnosis of special strabismus. Despite the importance of versions, they are not standardized in clinical practice because they are subjective. Assuming that objectivity confers accuracy, this research aims to create an artificial intelligence app that can classify the eye versions into nine positions of gaze. METHODS: We analyzed photos of 110 strabismus patients from an outpatient clinic of a tertiary hospital at nine gazes. For each photo, the gaze was identified, and the corresponding version was rated by the same examiner during patient evaluation. RESULTS: The images were standardized by using the OpenCV library in Python language, so that the patient's eyes were located and sent to a multilabel model through the Keras framework regardless of the photo orientation. Then, the model was trained for each combination of the following groupings: eyes (left, right), gaze (1 to 9), and version (−4 to 4). Resnet50 was used as the neural network architecture, and the Data Augmentation technique was applied. For quick inference via web browser, the SteamLit app framework was employed. For use in Mobiles, the finished model was exported for use in through the Tensorflow Lite converter. CONCLUSIONS: The results showed that the mobile app might be applied to complement evaluation of ocular motility based on objective classification of ocular versions. However, further exploratory research and validations are required. TRANSLATIONAL RELEVANCE: Apart from the traditional clinical practice method, professionals will be able to envisage an easy-to-apply support app, to increase diagnostic accuracy. The Association for Research in Vision and Ophthalmology 2021-06-17 /pmc/articles/PMC8212438/ /pubmed/34137838 http://dx.doi.org/10.1167/tvst.10.7.22 Text en Copyright 2021 The Authors https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License.
spellingShingle Article
de Figueiredo, Laura Alves
Dias, João Victor Pacheco
Polati, Mariza
Carricondo, Pedro Carlos
Debert, Iara
Strabismus and Artificial Intelligence App: Optimizing Diagnostic and Accuracy
title Strabismus and Artificial Intelligence App: Optimizing Diagnostic and Accuracy
title_full Strabismus and Artificial Intelligence App: Optimizing Diagnostic and Accuracy
title_fullStr Strabismus and Artificial Intelligence App: Optimizing Diagnostic and Accuracy
title_full_unstemmed Strabismus and Artificial Intelligence App: Optimizing Diagnostic and Accuracy
title_short Strabismus and Artificial Intelligence App: Optimizing Diagnostic and Accuracy
title_sort strabismus and artificial intelligence app: optimizing diagnostic and accuracy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212438/
https://www.ncbi.nlm.nih.gov/pubmed/34137838
http://dx.doi.org/10.1167/tvst.10.7.22
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