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Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma

BACKGROUND: Elevated transforming growth factor (TGF)-β2 in aqueous humor (AH) has been suggested to contribute to trabecular meshwork (TM) fibrosis and intraocular pressure (IOP) regulation in primary open-angle glaucoma (POAG), but TGF-β2 is downregulated in secondary open-angle glaucoma (SOAG). B...

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Detalles Bibliográficos
Autores principales: Igarashi, Nozomi, Honjo, Megumi, Yamagishi, Reiko, Kurano, Makoto, Yatomi, Yutaka, Igarashi, Koji, Kaburaki, Toshikatsu, Aihara, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212476/
https://www.ncbi.nlm.nih.gov/pubmed/34140021
http://dx.doi.org/10.1186/s12929-021-00745-3

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