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Estradiol regulates intestinal ABCG2 to promote urate excretion via the PI3K/Akt pathway

OBJECTIVES: The study of sex differences in hyperuricemia can provide not only a theoretical basis for this clinical phenomenon but also new therapeutic targets for urate-lowering therapy. In the current study, we aimed to confirm that estradiol can promote intestinal ATP binding cassette subfamily...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Zhao, Tianyi, Shan, Lizhen, Cao, Ling, Zhu, Xiaoxia, Xue, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212495/
https://www.ncbi.nlm.nih.gov/pubmed/34144706
http://dx.doi.org/10.1186/s12986-021-00583-y