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Mechanistic insights into mitochondrial tRNA(Ala) 3’-end metabolism deficiency
Mitochondrial tRNA 3’-end metabolism is critical for the formation of functional tRNAs. Deficient mitochondrial tRNA 3’-end metabolism is linked to an array of human diseases, including optic neuropathy, but their pathophysiology remains poorly understood. In this report, we investigated the molecul...
Autores principales: | Ji, Yanchun, Nie, Zhipeng, Meng, Feilong, Hu, Cuifang, Chen, Hui, Jin, Lihao, Chen, Mengquan, Zhang, Minglian, Zhang, Juanjuan, Liang, Min, Wang, Meng, Guan, Min-Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212662/ https://www.ncbi.nlm.nih.gov/pubmed/34023389 http://dx.doi.org/10.1016/j.jbc.2021.100816 |
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