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Hypoplasia of abdominal wall muscles following massive fetal persistent chylous ascites without anemia

Abdominal wall hypoplasia is a widely known clinical finding of genetic disorders such as the prune belly syndrome. On the other hand, there are few cases of abdominal wall muscle hypoplasia associated with fetal ascites due to fetal hydrops caused by fetal anemia have been reported. We report a cas...

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Autores principales: Yamaguchi, Tetsu, Tamaru, Shunsuke, Takano, Natsuko, Sato, Kazuko, Sakurai, Hayato, Ohashi, Hirofumi, Kamei, Yoshimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212683/
https://www.ncbi.nlm.nih.gov/pubmed/34158955
http://dx.doi.org/10.1093/omcr/omab039
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author Yamaguchi, Tetsu
Tamaru, Shunsuke
Takano, Natsuko
Sato, Kazuko
Sakurai, Hayato
Ohashi, Hirofumi
Kamei, Yoshimasa
author_facet Yamaguchi, Tetsu
Tamaru, Shunsuke
Takano, Natsuko
Sato, Kazuko
Sakurai, Hayato
Ohashi, Hirofumi
Kamei, Yoshimasa
author_sort Yamaguchi, Tetsu
collection PubMed
description Abdominal wall hypoplasia is a widely known clinical finding of genetic disorders such as the prune belly syndrome. On the other hand, there are few cases of abdominal wall muscle hypoplasia associated with fetal ascites due to fetal hydrops caused by fetal anemia have been reported. We report a case of fetal chylous ascites without anemia, resulting in abdominal wall muscle hypoplasia and flabby skin. At 17 weeks of gestation, fetal ascites was first detected and deteriorated without anemia. At 28, 33 and 36 weeks of gestation, paracentesis was performed three times because of cardiovascular impairment, confirming chylous ascites. After birth, the baby exhibited a flabby skin and lateral abdominal wall hypoplasia, resulting in difficulties in maintaining a sitting posture at 10 months of age. The genetic test using the TruSight One Sequencing Panels found no genetic variants. This case suggests that abdominal wall hypoplasia could be associated with fetal ascites without anemia.
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spelling pubmed-82126832021-06-21 Hypoplasia of abdominal wall muscles following massive fetal persistent chylous ascites without anemia Yamaguchi, Tetsu Tamaru, Shunsuke Takano, Natsuko Sato, Kazuko Sakurai, Hayato Ohashi, Hirofumi Kamei, Yoshimasa Oxf Med Case Reports Case Report Abdominal wall hypoplasia is a widely known clinical finding of genetic disorders such as the prune belly syndrome. On the other hand, there are few cases of abdominal wall muscle hypoplasia associated with fetal ascites due to fetal hydrops caused by fetal anemia have been reported. We report a case of fetal chylous ascites without anemia, resulting in abdominal wall muscle hypoplasia and flabby skin. At 17 weeks of gestation, fetal ascites was first detected and deteriorated without anemia. At 28, 33 and 36 weeks of gestation, paracentesis was performed three times because of cardiovascular impairment, confirming chylous ascites. After birth, the baby exhibited a flabby skin and lateral abdominal wall hypoplasia, resulting in difficulties in maintaining a sitting posture at 10 months of age. The genetic test using the TruSight One Sequencing Panels found no genetic variants. This case suggests that abdominal wall hypoplasia could be associated with fetal ascites without anemia. Oxford University Press 2021-06-18 /pmc/articles/PMC8212683/ /pubmed/34158955 http://dx.doi.org/10.1093/omcr/omab039 Text en © The Author(s) 2021. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Yamaguchi, Tetsu
Tamaru, Shunsuke
Takano, Natsuko
Sato, Kazuko
Sakurai, Hayato
Ohashi, Hirofumi
Kamei, Yoshimasa
Hypoplasia of abdominal wall muscles following massive fetal persistent chylous ascites without anemia
title Hypoplasia of abdominal wall muscles following massive fetal persistent chylous ascites without anemia
title_full Hypoplasia of abdominal wall muscles following massive fetal persistent chylous ascites without anemia
title_fullStr Hypoplasia of abdominal wall muscles following massive fetal persistent chylous ascites without anemia
title_full_unstemmed Hypoplasia of abdominal wall muscles following massive fetal persistent chylous ascites without anemia
title_short Hypoplasia of abdominal wall muscles following massive fetal persistent chylous ascites without anemia
title_sort hypoplasia of abdominal wall muscles following massive fetal persistent chylous ascites without anemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212683/
https://www.ncbi.nlm.nih.gov/pubmed/34158955
http://dx.doi.org/10.1093/omcr/omab039
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