Discovery of a Highly Conserved Peptide in the Iron Transporter Melanotransferrin that Traverses an Intact Blood Brain Barrier and Localizes in Neural Cells

The blood-brain barrier (BBB) hinders the distribution of therapeutics intended for treatment of diseases of the brain. Our previous studies demonstrated that that a soluble form of melanotransferrin (MTf; Uniprot P08582; also known as p97, MFI2, and CD228), a mammalian iron-transport protein, is an...

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Detalles Bibliográficos
Autores principales: Singh, Chaahat S. B., Eyford, Brett A., Abraham, Thomas, Munro, Lonna, Choi, Kyung Bok, Okon, Mark, Vitalis, Timothy Z., Gabathuler, Reinhard, Lu, Chieh-Ju, Pfeifer, Cheryl G., Tian, Mei Mei, Jefferies, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212695/
https://www.ncbi.nlm.nih.gov/pubmed/34149342
http://dx.doi.org/10.3389/fnins.2021.596976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212695/
https://www.ncbi.nlm.nih.gov/pubmed/34149342
http://dx.doi.org/10.3389/fnins.2021.596976

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