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Clinical significance of interventional therapeutic bronchoscopy combined with bronchial arterial embolization in the treatment of hypervascular primary airway tumors in children

IMPORTANCE: Pediatric hypervascular primary airway tumors are progressive, fatal lesions with a low incidence, and the disease is often more serious than that in adults. OBJECTIVE: To evaluate the clinical efficacy and safety of interventional therapeutic bronchoscopy combined with conservative trea...

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Autores principales: Yang, Haiming, Yin, Jie, Tang, Xiaolei, Li, Gan, Li, Huimin, Zhao, Shunying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212720/
https://www.ncbi.nlm.nih.gov/pubmed/34179710
http://dx.doi.org/10.1002/ped4.12256
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author Yang, Haiming
Yin, Jie
Tang, Xiaolei
Li, Gan
Li, Huimin
Zhao, Shunying
author_facet Yang, Haiming
Yin, Jie
Tang, Xiaolei
Li, Gan
Li, Huimin
Zhao, Shunying
author_sort Yang, Haiming
collection PubMed
description IMPORTANCE: Pediatric hypervascular primary airway tumors are progressive, fatal lesions with a low incidence, and the disease is often more serious than that in adults. OBJECTIVE: To evaluate the clinical efficacy and safety of interventional therapeutic bronchoscopy combined with conservative treatment and bronchial arterial embolization in children with primary airway tumors. METHODS: We retrospectively analyzed the clinical data of four pediatric patients with hypervascular primary airway tumor between 2017 and 2019 at Beijing Children’s Hospital. RESULTS: Two patients were low‐grade bronchial mucoepidermoid carcinoma, one patient was pleomorphic adenoma, and one was bronchial leiomyoma. Interventional therapeutic bronchoscopy combined with bronchial arterial embolization was used for treatment (all four patients received general anesthesia). The tumors were safely resected in all patients via interventional bronchoscopy. There were no severe complications related to the procedures. All patients were followed up for 5–12 months, and one low‐grade bronchial mucoepidermoid carcinoma recurred. INTERPRETATION: Interventional therapeutic bronchoscopy combined with bronchial arterial embolization appears to be a safe and efficient therapeutic method associated with less trauma and fewer complications, including no serious adverse events, in children with hypervascular primary airway tumors without bronchus wall infiltration.
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spelling pubmed-82127202021-06-25 Clinical significance of interventional therapeutic bronchoscopy combined with bronchial arterial embolization in the treatment of hypervascular primary airway tumors in children Yang, Haiming Yin, Jie Tang, Xiaolei Li, Gan Li, Huimin Zhao, Shunying Pediatr Investig Clinical Experience IMPORTANCE: Pediatric hypervascular primary airway tumors are progressive, fatal lesions with a low incidence, and the disease is often more serious than that in adults. OBJECTIVE: To evaluate the clinical efficacy and safety of interventional therapeutic bronchoscopy combined with conservative treatment and bronchial arterial embolization in children with primary airway tumors. METHODS: We retrospectively analyzed the clinical data of four pediatric patients with hypervascular primary airway tumor between 2017 and 2019 at Beijing Children’s Hospital. RESULTS: Two patients were low‐grade bronchial mucoepidermoid carcinoma, one patient was pleomorphic adenoma, and one was bronchial leiomyoma. Interventional therapeutic bronchoscopy combined with bronchial arterial embolization was used for treatment (all four patients received general anesthesia). The tumors were safely resected in all patients via interventional bronchoscopy. There were no severe complications related to the procedures. All patients were followed up for 5–12 months, and one low‐grade bronchial mucoepidermoid carcinoma recurred. INTERPRETATION: Interventional therapeutic bronchoscopy combined with bronchial arterial embolization appears to be a safe and efficient therapeutic method associated with less trauma and fewer complications, including no serious adverse events, in children with hypervascular primary airway tumors without bronchus wall infiltration. John Wiley and Sons Inc. 2021-06-18 /pmc/articles/PMC8212720/ /pubmed/34179710 http://dx.doi.org/10.1002/ped4.12256 Text en © 2021 Chinese Medical Association. Pediatric Investigation published by John Wiley & Sons Australia, Ltd on behalf of Futang Research Center of Pediatric Development. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Clinical Experience
Yang, Haiming
Yin, Jie
Tang, Xiaolei
Li, Gan
Li, Huimin
Zhao, Shunying
Clinical significance of interventional therapeutic bronchoscopy combined with bronchial arterial embolization in the treatment of hypervascular primary airway tumors in children
title Clinical significance of interventional therapeutic bronchoscopy combined with bronchial arterial embolization in the treatment of hypervascular primary airway tumors in children
title_full Clinical significance of interventional therapeutic bronchoscopy combined with bronchial arterial embolization in the treatment of hypervascular primary airway tumors in children
title_fullStr Clinical significance of interventional therapeutic bronchoscopy combined with bronchial arterial embolization in the treatment of hypervascular primary airway tumors in children
title_full_unstemmed Clinical significance of interventional therapeutic bronchoscopy combined with bronchial arterial embolization in the treatment of hypervascular primary airway tumors in children
title_short Clinical significance of interventional therapeutic bronchoscopy combined with bronchial arterial embolization in the treatment of hypervascular primary airway tumors in children
title_sort clinical significance of interventional therapeutic bronchoscopy combined with bronchial arterial embolization in the treatment of hypervascular primary airway tumors in children
topic Clinical Experience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212720/
https://www.ncbi.nlm.nih.gov/pubmed/34179710
http://dx.doi.org/10.1002/ped4.12256
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