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Gene therapy for diabetic peripheral neuropathy: A randomized, placebo‐controlled phase III study of VM202, a plasmid DNA encoding human hepatocyte growth factor
ABSTRACT: VM202 is a plasmid DNA encoding two isoforms of hepatocyte growth factor (HGF). A previous phase II study in subjects with painful diabetic peripheral neuropathy (DPN) showed significant reductions in pain. A phase III study was conducted to evaluate the safety and efficacy of VM202 in DPN...
Autores principales: | Kessler, John A., Shaibani, Aziz, Sang, Christine N., Christiansen, Mark, Kudrow, David, Vinik, Aaron, Shin, Nari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212761/ https://www.ncbi.nlm.nih.gov/pubmed/33465273 http://dx.doi.org/10.1111/cts.12977 |
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