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Preclinical animal studies in ischemic stroke: Challenges and some solutions

Despite the impressive efficacies demonstrated in preclinical research, hundreds of potentially neuroprotective drugs have failed to provide effective neuroprotection for ischemic stroke in human clinical trials. Lack of a powerful animal model for human ischemic stroke could be a major reason for t...

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Detalles Bibliográficos
Autores principales: Narayan, Sunil K., Grace Cherian, Simy, Babu Phaniti, Prakash, Babu Chidambaram, Saravana, Rachel Vasanthi, A. Hannah, Arumugam, Murugesan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212819/
https://www.ncbi.nlm.nih.gov/pubmed/34179718
http://dx.doi.org/10.1002/ame2.12166