Effect of Denosumab or Alendronic Acid on the Progression of Aortic Stenosis: A Double-Blind Randomized Controlled Trial

Valvular calcification is central to the pathogenesis and progression of aortic stenosis, with preclinical and observational studies suggesting that bone turnover and osteoblastic differentiation of valvular interstitial cells are important contributory mechanisms. We aimed to establish whether inhi...

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Detalles Bibliográficos
Autores principales: Pawade, Tania A., Doris, Mhairi K., Bing, Rong, White, Audrey C., Forsyth, Laura, Evans, Emily, Graham, Catriona, Williams, Michelle C., van Beek, Edwin J.R., Fletcher, Alison, Adamson, Philip D., Andrews, Jack P.M., Cartlidge, Timothy R.G., Jenkins, William S.A., Syed, Maaz, Fujisawa, Takeshi, Lucatelli, Christophe, Fraser, William, Ralston, Stuart H., Boon, Nicholas, Prendergast, Bernard, Newby, David E., Dweck, Marc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212878/
https://www.ncbi.nlm.nih.gov/pubmed/33913339
http://dx.doi.org/10.1161/CIRCULATIONAHA.121.053708

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