Cargando…

A Rare Case of Statin-Induced Diplopia: An Often-Overlooked but Reported Side Effect

Statins are a class of medications indicated for atherosclerotic cardiovascular diseases and dyslipidemia. Ever since their introduction, various side effects have been reported with their use. Statin-induced myopathy is a well-established side effect of the medication, ranging in severity from mild...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdelmasih, Randa, Abdelmaseih, Ramy, Reed, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212909/
https://www.ncbi.nlm.nih.gov/pubmed/34159019
http://dx.doi.org/10.7759/cureus.15117
_version_ 1783709728242663424
author Abdelmasih, Randa
Abdelmaseih, Ramy
Reed, Justin
author_facet Abdelmasih, Randa
Abdelmaseih, Ramy
Reed, Justin
author_sort Abdelmasih, Randa
collection PubMed
description Statins are a class of medications indicated for atherosclerotic cardiovascular diseases and dyslipidemia. Ever since their introduction, various side effects have been reported with their use. Statin-induced myopathy is a well-established side effect of the medication, ranging in severity from mild myotoxicity to fatal rhabdomyolysis, with or without an increase in creatine kinase levels. Statin-induced diplopia, ptosis, or ophthalmoplegia are very rare, but they have been reported as adverse events in a handful of cases. These adverse events typically result from the progressive weakening of the external ocular musculature or the levator palpebrae superioris muscle. In this report, we present a rare case of statin-induced diplopia in a patient who had been on atorvastatin therapy for years. We believe this report will increase awareness among physicians about such an adverse event related to statins.
format Online
Article
Text
id pubmed-8212909
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-82129092021-06-21 A Rare Case of Statin-Induced Diplopia: An Often-Overlooked but Reported Side Effect Abdelmasih, Randa Abdelmaseih, Ramy Reed, Justin Cureus Endocrinology/Diabetes/Metabolism Statins are a class of medications indicated for atherosclerotic cardiovascular diseases and dyslipidemia. Ever since their introduction, various side effects have been reported with their use. Statin-induced myopathy is a well-established side effect of the medication, ranging in severity from mild myotoxicity to fatal rhabdomyolysis, with or without an increase in creatine kinase levels. Statin-induced diplopia, ptosis, or ophthalmoplegia are very rare, but they have been reported as adverse events in a handful of cases. These adverse events typically result from the progressive weakening of the external ocular musculature or the levator palpebrae superioris muscle. In this report, we present a rare case of statin-induced diplopia in a patient who had been on atorvastatin therapy for years. We believe this report will increase awareness among physicians about such an adverse event related to statins. Cureus 2021-05-19 /pmc/articles/PMC8212909/ /pubmed/34159019 http://dx.doi.org/10.7759/cureus.15117 Text en Copyright © 2021, Abdelmasih et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Abdelmasih, Randa
Abdelmaseih, Ramy
Reed, Justin
A Rare Case of Statin-Induced Diplopia: An Often-Overlooked but Reported Side Effect
title A Rare Case of Statin-Induced Diplopia: An Often-Overlooked but Reported Side Effect
title_full A Rare Case of Statin-Induced Diplopia: An Often-Overlooked but Reported Side Effect
title_fullStr A Rare Case of Statin-Induced Diplopia: An Often-Overlooked but Reported Side Effect
title_full_unstemmed A Rare Case of Statin-Induced Diplopia: An Often-Overlooked but Reported Side Effect
title_short A Rare Case of Statin-Induced Diplopia: An Often-Overlooked but Reported Side Effect
title_sort rare case of statin-induced diplopia: an often-overlooked but reported side effect
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212909/
https://www.ncbi.nlm.nih.gov/pubmed/34159019
http://dx.doi.org/10.7759/cureus.15117
work_keys_str_mv AT abdelmasihranda ararecaseofstatininduceddiplopiaanoftenoverlookedbutreportedsideeffect
AT abdelmaseihramy ararecaseofstatininduceddiplopiaanoftenoverlookedbutreportedsideeffect
AT reedjustin ararecaseofstatininduceddiplopiaanoftenoverlookedbutreportedsideeffect
AT abdelmasihranda rarecaseofstatininduceddiplopiaanoftenoverlookedbutreportedsideeffect
AT abdelmaseihramy rarecaseofstatininduceddiplopiaanoftenoverlookedbutreportedsideeffect
AT reedjustin rarecaseofstatininduceddiplopiaanoftenoverlookedbutreportedsideeffect