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Targeted Deletion of Loxl3 by Col2a1-Cre Leads to Progressive Hearing Loss
Collagens are major constituents of the extracellular matrix (ECM) that play an essential role in the structure of the inner ear and provide elasticity and rigidity when the signals of sound are received and transformed into electrical signals. LOXL3 is a member of the lysyl oxidase (LOX) family tha...
Autores principales: | Liu, Ziyi, Bai, Xinfeng, Wan, Peifeng, Mo, Fan, Chen, Ge, Zhang, Jian, Gao, Jiangang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212933/ https://www.ncbi.nlm.nih.gov/pubmed/34150778 http://dx.doi.org/10.3389/fcell.2021.683495 |
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