Circulating and Tumor-Infiltrating NK Cells From Clear Cell Renal Cell Carcinoma Patients Exhibit a Predominantly Inhibitory Phenotype Characterized by Overexpression of CD85j, CD45, CD48 and PD-1

Although natural killer (NK) cells infiltrate clear cell renal cell carcinomas (ccRCC), the most frequent malignancy of the kidney, tumor progression suggests that they become dysfunctional. As ccRCC-driven subversion of NK cell effector functions is usually accompanied by phenotypic changes, analys...

Descripción completa

Detalles Bibliográficos
Autores principales: Ziblat, Andrea, Iraolagoitia, Ximena Lucía Raffo, Nuñez, Sol Yanel, Torres, Nicolás Ignacio, Secchiari, Florencia, Sierra, Jessica Mariel, Spallanzani, Raúl Germán, Rovegno, Agustín, Secin, Fernando Pablo, Fuertes, Mercedes Beatriz, Domaica, Carolina Inés, Zwirner, Norberto Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212993/
https://www.ncbi.nlm.nih.gov/pubmed/34149719
http://dx.doi.org/10.3389/fimmu.2021.681615

Ejemplares similares

Ejemplares similares