Cargando…

Predicting malaria epidemics in Burkina Faso with machine learning

Accurately forecasting the case rate of malaria would enable key decision makers to intervene months before the onset of any outbreak, potentially saving lives. Until now, methods that forecast malaria have involved complicated numerical simulations that model transmission through a community. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Harvey, David, Valkenburg, Wessel, Amara, Amara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213140/
https://www.ncbi.nlm.nih.gov/pubmed/34143829
http://dx.doi.org/10.1371/journal.pone.0253302
_version_ 1783709779106988032
author Harvey, David
Valkenburg, Wessel
Amara, Amara
author_facet Harvey, David
Valkenburg, Wessel
Amara, Amara
author_sort Harvey, David
collection PubMed
description Accurately forecasting the case rate of malaria would enable key decision makers to intervene months before the onset of any outbreak, potentially saving lives. Until now, methods that forecast malaria have involved complicated numerical simulations that model transmission through a community. Here we present the first data-driven malaria epidemic early warning system that can predict the 13-week case rate in a primary health facility in Burkina Faso. Using the extraordinarily high-fidelity data of infant consultations taken from the Integrated e-Diagnostic Approach (IeDA) system that has been rolled out throughout Burkina Faso, we train a combination of Gaussian Processes and Random Forest Regressors to estimate the weekly number of malaria cases over a 13 week period. We test our algorithm on historical epidemics and find that for our lowest threshold for an epidemic alert, our algorithm has 30% precision with > 99% recall at raising an alert. This rises to > 99% precision and 5% recall for the high alert threshold. Our two-tailed predictions have an average 1σ and 2σ precision of 5 cases and 30 cases respectively.
format Online
Article
Text
id pubmed-8213140
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-82131402021-06-29 Predicting malaria epidemics in Burkina Faso with machine learning Harvey, David Valkenburg, Wessel Amara, Amara PLoS One Research Article Accurately forecasting the case rate of malaria would enable key decision makers to intervene months before the onset of any outbreak, potentially saving lives. Until now, methods that forecast malaria have involved complicated numerical simulations that model transmission through a community. Here we present the first data-driven malaria epidemic early warning system that can predict the 13-week case rate in a primary health facility in Burkina Faso. Using the extraordinarily high-fidelity data of infant consultations taken from the Integrated e-Diagnostic Approach (IeDA) system that has been rolled out throughout Burkina Faso, we train a combination of Gaussian Processes and Random Forest Regressors to estimate the weekly number of malaria cases over a 13 week period. We test our algorithm on historical epidemics and find that for our lowest threshold for an epidemic alert, our algorithm has 30% precision with > 99% recall at raising an alert. This rises to > 99% precision and 5% recall for the high alert threshold. Our two-tailed predictions have an average 1σ and 2σ precision of 5 cases and 30 cases respectively. Public Library of Science 2021-06-18 /pmc/articles/PMC8213140/ /pubmed/34143829 http://dx.doi.org/10.1371/journal.pone.0253302 Text en © 2021 Harvey et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Harvey, David
Valkenburg, Wessel
Amara, Amara
Predicting malaria epidemics in Burkina Faso with machine learning
title Predicting malaria epidemics in Burkina Faso with machine learning
title_full Predicting malaria epidemics in Burkina Faso with machine learning
title_fullStr Predicting malaria epidemics in Burkina Faso with machine learning
title_full_unstemmed Predicting malaria epidemics in Burkina Faso with machine learning
title_short Predicting malaria epidemics in Burkina Faso with machine learning
title_sort predicting malaria epidemics in burkina faso with machine learning
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213140/
https://www.ncbi.nlm.nih.gov/pubmed/34143829
http://dx.doi.org/10.1371/journal.pone.0253302
work_keys_str_mv AT harveydavid predictingmalariaepidemicsinburkinafasowithmachinelearning
AT valkenburgwessel predictingmalariaepidemicsinburkinafasowithmachinelearning
AT amaraamara predictingmalariaepidemicsinburkinafasowithmachinelearning