Control of intestinal inflammation by glycosylation-dependent lectin-driven immunoregulatory circuits

Diverse immunoregulatory circuits operate to preserve intestinal homeostasis and prevent inflammation. Galectin-1 (Gal1), a β-galactoside–binding protein, promotes homeostasis by reprogramming innate and adaptive immunity. Here, we identify a glycosylation-dependent “on-off” circuit driven by Gal1 a...

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Detalles Bibliográficos
Autores principales: Morosi, Luciano G., Cutine, Anabela M., Cagnoni, Alejandro J., Manselle-Cocco, Montana N., Croci, Diego O., Merlo, Joaquín P., Morales, Rosa M., May, María, Pérez-Sáez, Juan M., Girotti, María R., Méndez-Huergo, Santiago P., Pucci, Betiana, Gil, Aníbal H., Huernos, Sergio P., Docena, Guillermo H., Sambuelli, Alicia M., Toscano, Marta A., Rabinovich, Gabriel A., Mariño, Karina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213219/
https://www.ncbi.nlm.nih.gov/pubmed/34144987
http://dx.doi.org/10.1126/sciadv.abf8630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213219/
https://www.ncbi.nlm.nih.gov/pubmed/34144987
http://dx.doi.org/10.1126/sciadv.abf8630

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