Cargando…

Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution

Similar forms often evolve repeatedly in nature, raising long-standing questions about the underlying mechanisms. Here, we use repeated evolution in stickleback to identify a large set of genomic loci that change recurrently during colonization of freshwater habitats by marine fish. The same loci us...

Descripción completa

Detalles Bibliográficos
Autores principales: Roberts Kingman, Garrett A., Vyas, Deven N., Jones, Felicity C., Brady, Shannon D., Chen, Heidi I., Reid, Kerry, Milhaven, Mark, Bertino, Thomas S., Aguirre, Windsor E., Heins, David C., von Hippel, Frank A., Park, Peter J., Kirch, Melanie, Absher, Devin M., Myers, Richard M., Di Palma, Federica, Bell, Michael A., Kingsley, David M., Veeramah, Krishna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213234/
https://www.ncbi.nlm.nih.gov/pubmed/34144992
http://dx.doi.org/10.1126/sciadv.abg5285
_version_ 1783709800905834496
author Roberts Kingman, Garrett A.
Vyas, Deven N.
Jones, Felicity C.
Brady, Shannon D.
Chen, Heidi I.
Reid, Kerry
Milhaven, Mark
Bertino, Thomas S.
Aguirre, Windsor E.
Heins, David C.
von Hippel, Frank A.
Park, Peter J.
Kirch, Melanie
Absher, Devin M.
Myers, Richard M.
Di Palma, Federica
Bell, Michael A.
Kingsley, David M.
Veeramah, Krishna R.
author_facet Roberts Kingman, Garrett A.
Vyas, Deven N.
Jones, Felicity C.
Brady, Shannon D.
Chen, Heidi I.
Reid, Kerry
Milhaven, Mark
Bertino, Thomas S.
Aguirre, Windsor E.
Heins, David C.
von Hippel, Frank A.
Park, Peter J.
Kirch, Melanie
Absher, Devin M.
Myers, Richard M.
Di Palma, Federica
Bell, Michael A.
Kingsley, David M.
Veeramah, Krishna R.
author_sort Roberts Kingman, Garrett A.
collection PubMed
description Similar forms often evolve repeatedly in nature, raising long-standing questions about the underlying mechanisms. Here, we use repeated evolution in stickleback to identify a large set of genomic loci that change recurrently during colonization of freshwater habitats by marine fish. The same loci used repeatedly in extant populations also show rapid allele frequency changes when new freshwater populations are experimentally established from marine ancestors. Marked genotypic and phenotypic changes arise within 5 years, facilitated by standing genetic variation and linkage between adaptive regions. Both the speed and location of changes can be predicted using empirical observations of recurrence in natural populations or fundamental genomic features like allelic age, recombination rates, density of divergent loci, and overlap with mapped traits. A composite model trained on these stickleback features can also predict the location of key evolutionary loci in Darwin’s finches, suggesting that similar features are important for evolution across diverse taxa.
format Online
Article
Text
id pubmed-8213234
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher American Association for the Advancement of Science
record_format MEDLINE/PubMed
spelling pubmed-82132342021-06-28 Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution Roberts Kingman, Garrett A. Vyas, Deven N. Jones, Felicity C. Brady, Shannon D. Chen, Heidi I. Reid, Kerry Milhaven, Mark Bertino, Thomas S. Aguirre, Windsor E. Heins, David C. von Hippel, Frank A. Park, Peter J. Kirch, Melanie Absher, Devin M. Myers, Richard M. Di Palma, Federica Bell, Michael A. Kingsley, David M. Veeramah, Krishna R. Sci Adv Research Articles Similar forms often evolve repeatedly in nature, raising long-standing questions about the underlying mechanisms. Here, we use repeated evolution in stickleback to identify a large set of genomic loci that change recurrently during colonization of freshwater habitats by marine fish. The same loci used repeatedly in extant populations also show rapid allele frequency changes when new freshwater populations are experimentally established from marine ancestors. Marked genotypic and phenotypic changes arise within 5 years, facilitated by standing genetic variation and linkage between adaptive regions. Both the speed and location of changes can be predicted using empirical observations of recurrence in natural populations or fundamental genomic features like allelic age, recombination rates, density of divergent loci, and overlap with mapped traits. A composite model trained on these stickleback features can also predict the location of key evolutionary loci in Darwin’s finches, suggesting that similar features are important for evolution across diverse taxa. American Association for the Advancement of Science 2021-06-18 /pmc/articles/PMC8213234/ /pubmed/34144992 http://dx.doi.org/10.1126/sciadv.abg5285 Text en Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (https://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.
spellingShingle Research Articles
Roberts Kingman, Garrett A.
Vyas, Deven N.
Jones, Felicity C.
Brady, Shannon D.
Chen, Heidi I.
Reid, Kerry
Milhaven, Mark
Bertino, Thomas S.
Aguirre, Windsor E.
Heins, David C.
von Hippel, Frank A.
Park, Peter J.
Kirch, Melanie
Absher, Devin M.
Myers, Richard M.
Di Palma, Federica
Bell, Michael A.
Kingsley, David M.
Veeramah, Krishna R.
Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution
title Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution
title_full Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution
title_fullStr Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution
title_full_unstemmed Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution
title_short Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution
title_sort predicting future from past: the genomic basis of recurrent and rapid stickleback evolution
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213234/
https://www.ncbi.nlm.nih.gov/pubmed/34144992
http://dx.doi.org/10.1126/sciadv.abg5285
work_keys_str_mv AT robertskingmangarretta predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT vyasdevenn predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT jonesfelicityc predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT bradyshannond predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT chenheidii predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT reidkerry predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT milhavenmark predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT bertinothomass predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT aguirrewindsore predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT heinsdavidc predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT vonhippelfranka predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT parkpeterj predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT kirchmelanie predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT absherdevinm predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT myersrichardm predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT dipalmafederica predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT bellmichaela predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT kingsleydavidm predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution
AT veeramahkrishnar predictingfuturefrompastthegenomicbasisofrecurrentandrapidsticklebackevolution