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Age Related Response of Neonatal Rat Retinal Ganglion Cells to Reduced TrkB Signaling in vitro and in vivo

During development of retinofugal pathways there is naturally occurring cell death of at least 50% of retinal ganglion cells (RGCs). In rats, RGC death occurs over a protracted pre- and early postnatal period, the timing linked to the onset of axonal ingrowth into central visual targets. Gene expres...

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Detalles Bibliográficos
Autores principales: Beros, Jamie, Rodger, Jennifer, Harvey, Alan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213349/
https://www.ncbi.nlm.nih.gov/pubmed/34150766
http://dx.doi.org/10.3389/fcell.2021.671087