The molecular coupling between substrate recognition and ATP turnover in a AAA+ hexameric helicase loader

In many bacteria and eukaryotes, replication fork establishment requires the controlled loading of hexameric, ring-shaped helicases around DNA by AAA+(ATPases Associated with various cellular Activities) ATPases. How loading factors use ATP to control helicase deposition is poorly understood. Here,...

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Detalles Bibliográficos
Autores principales: Puri, Neha, Fernandez, Amy J, O'Shea Murray, Valerie L, McMillan, Sarah, Keck, James L, Berger, James M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213410/
https://www.ncbi.nlm.nih.gov/pubmed/34036936
http://dx.doi.org/10.7554/eLife.64232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213410/
https://www.ncbi.nlm.nih.gov/pubmed/34036936
http://dx.doi.org/10.7554/eLife.64232

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