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The molecular coupling between substrate recognition and ATP turnover in a AAA+ hexameric helicase loader
In many bacteria and eukaryotes, replication fork establishment requires the controlled loading of hexameric, ring-shaped helicases around DNA by AAA+(ATPases Associated with various cellular Activities) ATPases. How loading factors use ATP to control helicase deposition is poorly understood. Here,...
Autores principales: | Puri, Neha, Fernandez, Amy J, O'Shea Murray, Valerie L, McMillan, Sarah, Keck, James L, Berger, James M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213410/ https://www.ncbi.nlm.nih.gov/pubmed/34036936 http://dx.doi.org/10.7554/eLife.64232 |
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