Cargando…

Identification of the Main Active Components and Mechanism of Wang Bi Tablet in Treating Rheumatoid Arthritis Based on Integrative Pharmacology

Wang Bi tablet (WBT) is used to treat rheumatoid arthritis (RA) in China. We employed integrative pharmacology, including rapid analysis of chemical composition, pharmacological experiment, and network pharmacology analysis, to elucidate the active components and mechanism underlying the effect of W...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiao, Yuanyuan, Xu, Jia, Chen, Hong, Guo, Qiuyan, Deng, Xiaofang, Zhang, Tong, Zhang, Jingbo, Shi, Chenjing, Wang, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213436/ https://www.ncbi.nlm.nih.gov/pubmed/34149422 http://dx.doi.org/10.3389/fphar.2021.669551

Ejemplares similares

Network Pharmacology-Based Analysis on the Effects and Mechanism of the Wang-Bi Capsule for Rheumatoid Arthritis and Osteoarthritis
por: Wu, Shan-Shan, et al.
Publicado: (2022)

Clinical Evidence-Guided Anti-rheumatoid Arthritis Study of Shuji Tablet in Adjuvant-Induced Arthritis Rats and Mechanism Exploration via Network Pharmacological Approach
por: Dai, Weibo, et al.
Publicado: (2021)

A Novel Circulating miRNA-Based Model Predicts the Response to Tripterysium Glycosides Tablets: Moving Toward Model-Based Precision Medicine in Rheumatoid Arthritis
por: Zhang, Yanqiong, et al.
Publicado: (2018)

Clinical Practice Guideline for Tripterygium Glycosides/Tripterygium wilfordii Tablets in the Treatment of Rheumatoid Arthritis
por: Lin, Na, et al.
Publicado: (2021)

Wu-Tou Decoction in Rheumatoid Arthritis: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation
por: Guo, Qingqing, et al.
Publicado: (2017)

Pharmacokinetics-Based Chronoefficacy of Semen Strychni and Tripterygium Glycoside Tablet Against Rheumatoid Arthritis
por: Lin, Jingpan, et al.
Publicado: (2021)

Pharmacological effects and mechanisms of bee venom and its main components: Recent progress and perspective
por: Shi, Peiying, et al.
Publicado: (2022)

Dissecting the Molecular Mechanism of Wang-Bi Capsule in the Treatment of Experimental Rheumatoid Arthritis Based on Synovial Tissue Proteomic Analysis
por: Shu, Haiyang, et al.
Publicado: (2021)

Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation
por: Aihaiti, Yirixiati, et al.
Publicado: (2021)

Characterization of the Components and Pharmacological Effects of Mountain-Cultivated Ginseng and Garden Ginseng Based on the Integrative Pharmacology Strategy
por: Li, Sen, et al.
Publicado: (2021)

Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation
por: Shi, Lu, et al.
Publicado: (2022)

Tripterygium hypoglaucum (Lévl.) Hutch and Its Main Bioactive Components: Recent Advances in Pharmacological Activity, Pharmacokinetics and Potential Toxicity
por: Zhao, Junqi, et al.
Publicado: (2021)

An Integrative Pharmacology Model for Decoding the Underlying Therapeutic Mechanisms of Ermiao Powder for Rheumatoid Arthritis
por: Wu, Jie, et al.
Publicado: (2022)

Treatment of Rheumatoid Arthritis Using Combination of Methotrexate and Tripterygium Glycosides Tablets—A Quantitative Plasma Pharmacochemical and Pseudotargeted Metabolomic Approach
por: Wang, Menglei, et al.
Publicado: (2018)

Network Pharmacology-Based Prediction of Active Ingredients and Mechanisms of Lamiophlomis rotata (Benth.) Kudo Against Rheumatoid Arthritis
por: Jiang, Yunbin, et al.
Publicado: (2019)

The bone-protective mechanisms of active components from TCM drugs in rheumatoid arthritis treatment
por: Lu, Qingyi, et al.
Publicado: (2022)

Corrigendum: An integrative pharmacology model for decoding the underlying Therapeutic Mechanisms of Ermiao Powder for Rheumatoid arthritis
por: Wu, Jie, et al.
Publicado: (2023)

Wang-Bi Capsule Alleviates the Joint Inflammation and Bone Destruction in Mice with Collagen-Induced Arthritis
por: Cui, Hua, et al.
Publicado: (2020)

The effect of JuanBiQiangGu granules in combination with methotrexate on joint inflammation in rheumatoid arthritis: a randomized controlled trial
por: Ran, Lei, et al.
Publicado: (2023)

Network Pharmacology Based Research on the Combination Mechanism Between Escin and Low Dose Glucocorticoids in Anti-rheumatoid Arthritis
por: Zhang, Leiming, et al.
Publicado: (2019)

Network analysis combined with pharmacological evaluation strategy to reveal the mechanism of Tibetan medicine Wuwei Shexiang pills in treating rheumatoid arthritis
por: He, Qingxiu, et al.
Publicado: (2022)

Detecting potential mechanism of vitamin D in treating rheumatoid arthritis based on network pharmacology and molecular docking
por: Xu, Xiaoyu, et al.
Publicado: (2022)

Evaluating the Therapeutic Mechanisms of Selected Active Compounds in Cornus Officinalis and Paeonia Lactiflora in Rheumatoid Arthritis via Network Pharmacology Analysis
por: Li, Qinglin, et al.
Publicado: (2021)

Efficacy and Safety of TangWang Prescription for Type 2 Non-Proliferative Diabetic Retinopathy: A Study Protocol for a Randomized Controlled Trial
por: Jin, De, et al.
Publicado: (2021)

Gaultheria leucocarpa var. yunnanensis for Treating Rheumatoid Arthritis—An Assessment Combining Machine Learning–Guided ADME Properties Prediction, Network Pharmacology, and Pharmacological Assessment
por: Wang, Xiuhuan, et al.
Publicado: (2021)

Uncovering the Complexity Mechanism of Different Formulas Treatment for Rheumatoid Arthritis Based on a Novel Network Pharmacology Model
por: Wang, Ke-xin, et al.
Publicado: (2020)

Immunomodulatory roles of metalloproteinases in rheumatoid arthritis
por: Bian, Yanqin, et al.
Publicado: (2023)

Tripterygium Ingredients for Pathogenicity Cells in Rheumatoid Arthritis
por: Tang, Yujun, et al.
Publicado: (2020)

Integrated Serum and Fecal Metabolomics Study of Collagen-Induced Arthritis Rats and the Therapeutic Effects of the Zushima Tablet
por: Shan, Jinjun, et al.
Publicado: (2018)

Exploring Ganweikang Tablet as a Candidate Drug for NAFLD Through Network Pharmacology Analysis and Experimental Validation
por: Ma, Chuanrui, et al.
Publicado: (2022)

Identification of Tumor Necrosis Factor-Alpha (TNF-α) Inhibitor in Rheumatoid Arthritis Using Network Pharmacology and Molecular Docking
por: Bai, Liang Liang, et al.
Publicado: (2021)

Consistency of recommendations for pharmacotherapy of rheumatoid arthritis
por: Hu, Yue, et al.
Publicado: (2022)

Traditional Tibetan medicine: therapeutic potential in rheumatoid arthritis
por: Yu, Liqiong, et al.
Publicado: (2022)

Integrated Phytochemical Analysis Based on UPLC–MS/MS and Network Pharmacology Approaches to Explore the Effect of Odontites vulgaris Moench on Rheumatoid Arthritis
por: Ji, Mingyue, et al.
Publicado: (2021)

Tanshinones, Critical Pharmacological Components in Salvia miltiorrhiza
por: Jiang, Zhouqian, et al.
Publicado: (2019)

Transcriptomics‐based analysis of the mechanism by which Wang-Bi capsule alleviates joint destruction in rats with collagen‐induced arthritis
por: Shu, Haiyang, et al.
Publicado: (2021)

Pathogenesis and Function of Interleukin-35 in Rheumatoid Arthritis
por: Xin, Pan Lin, et al.
Publicado: (2021)

Nanomaterials Manipulate Macrophages for Rheumatoid Arthritis Treatment
por: Li, Shuang, et al.
Publicado: (2021)

A novel gene-expression-signature-based model for prediction of response to Tripterysium glycosides tablet for rheumatoid arthritis patients
por: Zhang, Yanqiong, et al.
Publicado: (2018)

Exploring the Therapeutic Composition and Mechanism of Jiang-Suan-Chu-Bi Recipe on Gouty Arthritis Using an Integrated Approach Based on Chemical Profile, Network Pharmacology and Experimental Support Using Molecular Cell Biology
por: Xiao, Nan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fa8v6rcn5sbv4kc8ektv60effp