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Cannabis alters epigenetic integrity and endocannabinoid signalling in the human follicular niche

STUDY QUESTION: Do phytocannabinoids (PCs) affect follicular endocannabinoid signalling and the epigenome in the surrounding granulosa cells (GCs)? SUMMARY ANSWER: Exposure to PCs increases the expression of endocannabinoid receptors and reduces DNA methylation enzyme expression and global DNA methy...

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Detalles Bibliográficos
Autores principales:	Fuchs Weizman, Noga, Wyse, Brandon A, Szaraz, Peter, Defer, Miranda, Jahangiri, Sahar, Librach, Clifford L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213445/ https://www.ncbi.nlm.nih.gov/pubmed/33954787 http://dx.doi.org/10.1093/humrep/deab104

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