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Caspase-1-Inhibitor AC-YVAD-CMK Inhibits Pyroptosis and Ameliorates Acute Kidney Injury in a Model of Sepsis

OBJECTIVE: To observe the protective effect of AC-YVAD-CMK on sepsis-induced acute kidney injury in mice and to explore its possible mechanisms primarily. METHODS: Eighteen male C57BL/6 mice were randomly divided into sham-operated group (Control), cecal ligation and puncture group (CLP), and CLP mo...

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Detalles Bibliográficos
Autores principales:	Yang, Mei, Fang, Jin-tao, Zhang, Ni-shang, Qin, Long-jiang, Zhuang, Yang-yang, Wang, Wei-wei, Zhu, Hai-ping, Zhang, Yan-jie, Xia, Peng, Zhang, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213477/ https://www.ncbi.nlm.nih.gov/pubmed/34222479 http://dx.doi.org/10.1155/2021/6636621

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