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The impact of lockdown strategies on the basic reproductive number of coronavirus (COVID-19) cases in Saudi Arabia

BACKGROUND & OBJECTIVES: In late December 2019, an outbreak of severe acute respiratory syndrome coronavirus 2 (SARS COV-2) occurred in the city of Wuhan, the capital of the Hubei province in the central part of the People’s Republic of China (Ren et al., 2020). In Saudi Arabia, the first case o...

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Autores principales: Ahmad Alajlan, Saleh, Alhusseini, Noara K., Mohammed Basheeruddin Asdaq, Syed, Mohzari, Yahya, Alamer, Ahmad, Alrashed, Ahmed A., Alamri, Abdulhakeem S., Alsanie, Walaa F., Alhomrani, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213511/
https://www.ncbi.nlm.nih.gov/pubmed/34177316
http://dx.doi.org/10.1016/j.sjbs.2021.06.047
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author Ahmad Alajlan, Saleh
Alhusseini, Noara K.
Mohammed Basheeruddin Asdaq, Syed
Mohzari, Yahya
Alamer, Ahmad
Alrashed, Ahmed A.
Alamri, Abdulhakeem S.
Alsanie, Walaa F.
Alhomrani, Majid
author_facet Ahmad Alajlan, Saleh
Alhusseini, Noara K.
Mohammed Basheeruddin Asdaq, Syed
Mohzari, Yahya
Alamer, Ahmad
Alrashed, Ahmed A.
Alamri, Abdulhakeem S.
Alsanie, Walaa F.
Alhomrani, Majid
author_sort Ahmad Alajlan, Saleh
collection PubMed
description BACKGROUND & OBJECTIVES: In late December 2019, an outbreak of severe acute respiratory syndrome coronavirus 2 (SARS COV-2) occurred in the city of Wuhan, the capital of the Hubei province in the central part of the People’s Republic of China (Ren et al., 2020). In Saudi Arabia, the first case of COVID-19 was reported in March 2, 2020. In March 8, 2020, the Saudi authorities adopted the lockdown strategy to contain the disease. The aim of this study was to determine the effectiveness of the various phases of the lockdown strategy in Saudi Arabia and its impact on the basic reproductive number (R0) of the COVID-19 outbreak. MATERIAL AND METHODS: The timeline of the COVID-19 outbreak in Saudi Arabia was divided into three-time intervals. Google Mobility Community Reports (2020) was used to estimate the changes in community mobility during the various phases of the lockdown. The basic reproductive number (R0) of the COVID-19 outbreak was calculated daily using the Susceptible, Infected and Recovered (SIR) model based on the Saudi Ministry of Health (MOH) daily reports. This is a standard system to determine the spread of the virus on the basis of infection rate, quarantine rate as well as confirmation rate. The mean values of the calculated R0 during each interval were compared using one-way ANOVA test. RESULTS: There was no statistically significant difference between the mean values of the different phases of the lockdown (P > 0.05). Moreover, mean R0 value of the second interval was 0.09 higher than the initial interval with free community mobility. Furthermore, the mean R0 values of the third interval with the full lockdown was 0.28 higher than the initial interval. CONCLUSION: Early implementation of lockdown strategy combined with other social distancing strategies help in containing infectious outbreaks in their early phases. Continuous assessment of such strategies’ effectiveness provides decision makers with precious information needed to justify their application when considering their economic impact.
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spelling pubmed-82135112021-06-21 The impact of lockdown strategies on the basic reproductive number of coronavirus (COVID-19) cases in Saudi Arabia Ahmad Alajlan, Saleh Alhusseini, Noara K. Mohammed Basheeruddin Asdaq, Syed Mohzari, Yahya Alamer, Ahmad Alrashed, Ahmed A. Alamri, Abdulhakeem S. Alsanie, Walaa F. Alhomrani, Majid Saudi J Biol Sci Original Article BACKGROUND & OBJECTIVES: In late December 2019, an outbreak of severe acute respiratory syndrome coronavirus 2 (SARS COV-2) occurred in the city of Wuhan, the capital of the Hubei province in the central part of the People’s Republic of China (Ren et al., 2020). In Saudi Arabia, the first case of COVID-19 was reported in March 2, 2020. In March 8, 2020, the Saudi authorities adopted the lockdown strategy to contain the disease. The aim of this study was to determine the effectiveness of the various phases of the lockdown strategy in Saudi Arabia and its impact on the basic reproductive number (R0) of the COVID-19 outbreak. MATERIAL AND METHODS: The timeline of the COVID-19 outbreak in Saudi Arabia was divided into three-time intervals. Google Mobility Community Reports (2020) was used to estimate the changes in community mobility during the various phases of the lockdown. The basic reproductive number (R0) of the COVID-19 outbreak was calculated daily using the Susceptible, Infected and Recovered (SIR) model based on the Saudi Ministry of Health (MOH) daily reports. This is a standard system to determine the spread of the virus on the basis of infection rate, quarantine rate as well as confirmation rate. The mean values of the calculated R0 during each interval were compared using one-way ANOVA test. RESULTS: There was no statistically significant difference between the mean values of the different phases of the lockdown (P > 0.05). Moreover, mean R0 value of the second interval was 0.09 higher than the initial interval with free community mobility. Furthermore, the mean R0 values of the third interval with the full lockdown was 0.28 higher than the initial interval. CONCLUSION: Early implementation of lockdown strategy combined with other social distancing strategies help in containing infectious outbreaks in their early phases. Continuous assessment of such strategies’ effectiveness provides decision makers with precious information needed to justify their application when considering their economic impact. Elsevier 2021-09 2021-06-19 /pmc/articles/PMC8213511/ /pubmed/34177316 http://dx.doi.org/10.1016/j.sjbs.2021.06.047 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Ahmad Alajlan, Saleh
Alhusseini, Noara K.
Mohammed Basheeruddin Asdaq, Syed
Mohzari, Yahya
Alamer, Ahmad
Alrashed, Ahmed A.
Alamri, Abdulhakeem S.
Alsanie, Walaa F.
Alhomrani, Majid
The impact of lockdown strategies on the basic reproductive number of coronavirus (COVID-19) cases in Saudi Arabia
title The impact of lockdown strategies on the basic reproductive number of coronavirus (COVID-19) cases in Saudi Arabia
title_full The impact of lockdown strategies on the basic reproductive number of coronavirus (COVID-19) cases in Saudi Arabia
title_fullStr The impact of lockdown strategies on the basic reproductive number of coronavirus (COVID-19) cases in Saudi Arabia
title_full_unstemmed The impact of lockdown strategies on the basic reproductive number of coronavirus (COVID-19) cases in Saudi Arabia
title_short The impact of lockdown strategies on the basic reproductive number of coronavirus (COVID-19) cases in Saudi Arabia
title_sort impact of lockdown strategies on the basic reproductive number of coronavirus (covid-19) cases in saudi arabia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213511/
https://www.ncbi.nlm.nih.gov/pubmed/34177316
http://dx.doi.org/10.1016/j.sjbs.2021.06.047
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