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Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl

Viral infections have a well-known influence on the pathophysiology of type 1 diabetes mellitus (T1DM). There is scant data about the impact of COVID-19 T1DM and diabetic ketoacidosis (DKA) on paediatric patients. This case presents a newly diagnosed paediatric patient with T1DM and DKA who was foun...

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Detalles Bibliográficos
Autores principales: Albuali, Waleed H., AlGhamdi, Nora A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taibah University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213538/
https://www.ncbi.nlm.nih.gov/pubmed/34177416
http://dx.doi.org/10.1016/j.jtumed.2021.01.011
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author Albuali, Waleed H.
AlGhamdi, Nora A.
author_facet Albuali, Waleed H.
AlGhamdi, Nora A.
author_sort Albuali, Waleed H.
collection PubMed
description Viral infections have a well-known influence on the pathophysiology of type 1 diabetes mellitus (T1DM). There is scant data about the impact of COVID-19 T1DM and diabetic ketoacidosis (DKA) on paediatric patients. This case presents a newly diagnosed paediatric patient with T1DM and DKA who was found to have SARS-CoV-2 without any respiratory symptoms. A 7-year-old girl presented with a history of polydipsia, polyuria, and weight loss. This presentation was complicated by a 2-day history of fatigue and vomiting. Investigations into the patient's condition confirmed T1DM with DKA. Following the infection control protocol, she underwent screening for SARS-CoV-2, which yielded a positive result. During her hospital stay, she did not develop fever or respiratory symptoms. The ketoacidosis was treated without any complications. We conclude that SARS-CoV-2 may trigger the onset of T1DM and may precipitate the occurrence of DKA in paediatric diabetic patients, even in the absence of respiratory symptoms.
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spelling pubmed-82135382021-06-21 Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl Albuali, Waleed H. AlGhamdi, Nora A. J Taibah Univ Med Sci Case Report Viral infections have a well-known influence on the pathophysiology of type 1 diabetes mellitus (T1DM). There is scant data about the impact of COVID-19 T1DM and diabetic ketoacidosis (DKA) on paediatric patients. This case presents a newly diagnosed paediatric patient with T1DM and DKA who was found to have SARS-CoV-2 without any respiratory symptoms. A 7-year-old girl presented with a history of polydipsia, polyuria, and weight loss. This presentation was complicated by a 2-day history of fatigue and vomiting. Investigations into the patient's condition confirmed T1DM with DKA. Following the infection control protocol, she underwent screening for SARS-CoV-2, which yielded a positive result. During her hospital stay, she did not develop fever or respiratory symptoms. The ketoacidosis was treated without any complications. We conclude that SARS-CoV-2 may trigger the onset of T1DM and may precipitate the occurrence of DKA in paediatric diabetic patients, even in the absence of respiratory symptoms. Taibah University 2021-02-16 /pmc/articles/PMC8213538/ /pubmed/34177416 http://dx.doi.org/10.1016/j.jtumed.2021.01.011 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Albuali, Waleed H.
AlGhamdi, Nora A.
Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl
title Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl
title_full Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl
title_fullStr Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl
title_full_unstemmed Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl
title_short Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl
title_sort diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213538/
https://www.ncbi.nlm.nih.gov/pubmed/34177416
http://dx.doi.org/10.1016/j.jtumed.2021.01.011
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