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Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl
Viral infections have a well-known influence on the pathophysiology of type 1 diabetes mellitus (T1DM). There is scant data about the impact of COVID-19 T1DM and diabetic ketoacidosis (DKA) on paediatric patients. This case presents a newly diagnosed paediatric patient with T1DM and DKA who was foun...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taibah University
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213538/ https://www.ncbi.nlm.nih.gov/pubmed/34177416 http://dx.doi.org/10.1016/j.jtumed.2021.01.011 |
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author | Albuali, Waleed H. AlGhamdi, Nora A. |
author_facet | Albuali, Waleed H. AlGhamdi, Nora A. |
author_sort | Albuali, Waleed H. |
collection | PubMed |
description | Viral infections have a well-known influence on the pathophysiology of type 1 diabetes mellitus (T1DM). There is scant data about the impact of COVID-19 T1DM and diabetic ketoacidosis (DKA) on paediatric patients. This case presents a newly diagnosed paediatric patient with T1DM and DKA who was found to have SARS-CoV-2 without any respiratory symptoms. A 7-year-old girl presented with a history of polydipsia, polyuria, and weight loss. This presentation was complicated by a 2-day history of fatigue and vomiting. Investigations into the patient's condition confirmed T1DM with DKA. Following the infection control protocol, she underwent screening for SARS-CoV-2, which yielded a positive result. During her hospital stay, she did not develop fever or respiratory symptoms. The ketoacidosis was treated without any complications. We conclude that SARS-CoV-2 may trigger the onset of T1DM and may precipitate the occurrence of DKA in paediatric diabetic patients, even in the absence of respiratory symptoms. |
format | Online Article Text |
id | pubmed-8213538 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Taibah University |
record_format | MEDLINE/PubMed |
spelling | pubmed-82135382021-06-21 Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl Albuali, Waleed H. AlGhamdi, Nora A. J Taibah Univ Med Sci Case Report Viral infections have a well-known influence on the pathophysiology of type 1 diabetes mellitus (T1DM). There is scant data about the impact of COVID-19 T1DM and diabetic ketoacidosis (DKA) on paediatric patients. This case presents a newly diagnosed paediatric patient with T1DM and DKA who was found to have SARS-CoV-2 without any respiratory symptoms. A 7-year-old girl presented with a history of polydipsia, polyuria, and weight loss. This presentation was complicated by a 2-day history of fatigue and vomiting. Investigations into the patient's condition confirmed T1DM with DKA. Following the infection control protocol, she underwent screening for SARS-CoV-2, which yielded a positive result. During her hospital stay, she did not develop fever or respiratory symptoms. The ketoacidosis was treated without any complications. We conclude that SARS-CoV-2 may trigger the onset of T1DM and may precipitate the occurrence of DKA in paediatric diabetic patients, even in the absence of respiratory symptoms. Taibah University 2021-02-16 /pmc/articles/PMC8213538/ /pubmed/34177416 http://dx.doi.org/10.1016/j.jtumed.2021.01.011 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Albuali, Waleed H. AlGhamdi, Nora A. Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl |
title | Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl |
title_full | Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl |
title_fullStr | Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl |
title_full_unstemmed | Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl |
title_short | Diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl |
title_sort | diabetic ketoacidosis precipitated by atypical coronavirus disease in a newly diagnosed diabetic girl |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213538/ https://www.ncbi.nlm.nih.gov/pubmed/34177416 http://dx.doi.org/10.1016/j.jtumed.2021.01.011 |
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