Safety and efficacy of panitumumab in combination with trifluridine/tipiracil for pre-treated patients with unresectable, metastatic colorectal cancer with wild-type RAS: The phase 1/2 APOLLON study

BACKGROUND: We aimed to assess the safety and efficacy of combination treatment with panitumumab plus trifluridine/tipiracil (FTD/TPI) in patients with wild-type RAS metastatic colorectal cancer (mCRC) who were refractory/intolerant to standard therapies other than anti-epidermal growth factor recep...

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Detalles Bibliográficos
Autores principales: Kato, Takeshi, Kagawa, Yoshinori, Kuboki, Yasutoshi, Gamoh, Makio, Komatsu, Yoshito, Yasui, Hirofumi, Satake, Hironaga, Oki, Eiji, Tanioka, Hiroaki, Kotaka, Masahito, Makiyama, Akitaka, Denda, Tadamichi, Goto, Masahiro, Yoshino, Takayuki, Yamazaki, Kentaro, Soeda, Junpei, Shibuya, Kazunori, Iwata, Masaru, Oba, Koji, Yamaguchi, Kensei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213662/
https://www.ncbi.nlm.nih.gov/pubmed/33928486
http://dx.doi.org/10.1007/s10147-021-01902-2

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