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Modelling the interplay between the CD4[Formula: see text] /CD8[Formula: see text] T-cell ratio and the expression of MHC-I in tumours
Describing the anti-tumour immune response as a series of cellular kinetic reactions from known immunological mechanisms, we create a mathematical model that shows the CD4[Formula: see text] /CD8[Formula: see text] T-cell ratio, T-cell infiltration and the expression of MHC-I to be interacting facto...
Autores principales: | Hurry, Christian John, Mozeika, Alexander, Annibale, Alessia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213681/ https://www.ncbi.nlm.nih.gov/pubmed/34143314 http://dx.doi.org/10.1007/s00285-021-01622-1 |
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