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Modelling the interplay between the CD4[Formula: see text] /CD8[Formula: see text] T-cell ratio and the expression of MHC-I in tumours

Describing the anti-tumour immune response as a series of cellular kinetic reactions from known immunological mechanisms, we create a mathematical model that shows the CD4[Formula: see text] /CD8[Formula: see text] T-cell ratio, T-cell infiltration and the expression of MHC-I to be interacting facto...

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Detalles Bibliográficos
Autores principales: Hurry, Christian John, Mozeika, Alexander, Annibale, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213681/
https://www.ncbi.nlm.nih.gov/pubmed/34143314
http://dx.doi.org/10.1007/s00285-021-01622-1

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