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Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells
Claudin-low breast cancer represents an aggressive molecular subtype that is comprised of mostly triple-negative mammary tumor cells that possess stem cell-like and mesenchymal features. Little is known about the cellular origin and oncogenic drivers that promote claudin-low breast cancer. In this s...
Autores principales: | Rädler, Patrick D., Wehde, Barbara L., Triplett, Aleata A., Shrestha, Hridaya, Shepherd, Jonathan H., Pfefferle, Adam D., Rui, Hallgeir, Cardiff, Robert D., Perou, Charles M., Wagner, Kay-Uwe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213728/ https://www.ncbi.nlm.nih.gov/pubmed/34145248 http://dx.doi.org/10.1038/s41467-021-23957-5 |
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