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Next generation proteomics with drug sensitivity screening identifies sub-clones informing therapeutic and drug development strategies for multiple myeloma patients

With the introduction of novel therapeutic agents, survival in Multiple Myeloma (MM) has increased in recent years. However, drug-resistant clones inevitably arise and lead to disease progression and death. The current International Myeloma Working Group response criteria are broad and make it diffi...

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Detalles Bibliográficos
Autores principales: Tierney, Ciara, Bazou, Despina, Majumder, Muntasir M., Anttila, Pekka, Silvennoinen, Raija, Heckman, Caroline A., Dowling, Paul, O’Gorman, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213739/
https://www.ncbi.nlm.nih.gov/pubmed/34145309
http://dx.doi.org/10.1038/s41598-021-90149-y