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Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors

Autism spectrum disorder (ASD) is a neurodevelopmental disease associated with various gene mutations. Recent genetic and clinical studies report that mutations of the epigenetic gene ASH1L are highly associated with human ASD and intellectual disability (ID). However, the causality and underlying m...

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Detalles Bibliográficos
Autores principales: Gao, Yuen, Duque-Wilckens, Natalia, Aljazi, Mohammad B., Wu, Yan, Moeser, Adam J., Mias, George I., Robison, Alfred J., He, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213741/
https://www.ncbi.nlm.nih.gov/pubmed/34145365
http://dx.doi.org/10.1038/s42003-021-02282-z