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Hypoxic postconditioning promotes mitophagy against transient global cerebral ischemia via PINK1/Parkin-induced mitochondrial ubiquitination in adult rats

Mitophagy alleviates neuronal damage after cerebral ischemia by selectively removing dysfunctional mitochondria. Phosphatase and tensin homolog (PTEN) induced putative kinase 1 (PINK1)/Parkin-mediated mitophagy is the most well-known type of mitophagy. However, little is known about the role of PINK...

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Detalles Bibliográficos
Autores principales:	Wen, Haixia, Li, Luxi, Zhan, Lixuan, Zuo, Yunyan, Li, Kongping, Qiu, Meiqian, Li, Heying, Sun, Weiwen, Xu, En
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213752/ https://www.ncbi.nlm.nih.gov/pubmed/34145219 http://dx.doi.org/10.1038/s41419-021-03900-8

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