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hsp-90 and unc-45 depletion induce characteristic transcriptional signatures in coexpression cliques of C. elegans
Nematode development is characterized by progression through several larval stages. Thousands of genes were found in large scale RNAi-experiments to block this development at certain steps, two of which target the molecular chaperone HSP-90 and its cofactor UNC-45. Aiming to define the cause of arre...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213770/ https://www.ncbi.nlm.nih.gov/pubmed/34145311 http://dx.doi.org/10.1038/s41598-021-91690-6 |