Arginine methylation of METTL14 promotes RNA N(6)-methyladenosine modification and endoderm differentiation of mouse embryonic stem cells

RNA N(6)-methyladenosine (m(6)A), the most abundant internal modification of mRNAs, plays key roles in human development and health. Post-translational methylation of proteins is often critical for the dynamic regulation of enzymatic activity. However, the role of methylation of the core methyltrans...

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Detalles Bibliográficos
Autores principales: Liu, Xiaona, Wang, Hailong, Zhao, Xueya, Luo, Qizhi, Wang, Qingwen, Tan, Kaifen, Wang, Zihan, Jiang, Jia, Cui, Jinru, Du, Enhui, Xia, Linjian, Du, Wenyi, Chen, Dahua, Xia, Laixin, Xiao, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213825/
https://www.ncbi.nlm.nih.gov/pubmed/34145242
http://dx.doi.org/10.1038/s41467-021-24035-6

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